Pargyline | definition of pargyline by Medical dictionary
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pargyline Eutonyl Pharmacology An MAOI with antidepressant activity; it is less effective than TCAs; it requires abstinence from foods with tyramine; interacts metabolically with other drugs; its use is limited to Pts unresponsive to TCAs and tetracyclic antidepressants and Pts with atypical depression. See Monoamine oxidase inhibitor, Tricyclic antidepressants.
a monoamine oxidase inhibitor, used as the hydrochloride salt.
References in periodicals archive
1,3-Ditolylguanidine (DTG), clozapine, GBR12909, pargyline
and dopamine were purchased from Sigma Chemical Co.
prevents MPTP-induced parkinsonism in primates.
Isoform-specific irreversible inhibitors include clorygline, which is a research compound specific for MAO-A, and the two B-selective inhibitors selegiline and pargyline
50] values of positive control, L-deprenyl (an MAO-B inhibitor) and pargyline
(a nonselective MAO inhibitor), were 0.