We've known that there are 95 genes that are subject to this parent-of-origin effect.
Studying them in genetically diverse mouse models that take parent-of-origin into account will give scientists more precise insights into the underlying causes of disease and the creation of therapeutics or other interventions.
POD QTL were tested with a series of tests to differentiate parent-of-origin effects (complete imprinting) from Mendelian effects.
Our simulation results strongly suggest that POD QTL be tested with the presented tests (2 and 3) to differentiate POD expression from parent-of-origin expression (complete imprinting).
Detection of Mendelian and parent-of-origin quantitative trait loci for meat quality in a cross between Korean native pig and Landrace.
The next three chapters present a detailed review of the molecular and statistical aspects of imprinted genes and parent-of-origin
effects on production traits.
Imprinting in Genome Analysis: Modeling Parent-of-Origin
Effects in QTL Studies
2007) performed genome scans to detect Mendelian and parent-of-origin QTL for growth and body composition traits in a cross population of KNP and Landrace.
For each chromosome, least squares interval mapping models were applied to detect Mendelian and parent-of-origin QTL.
Among the QTL, four QTL had parent-of-origin effects, while only one QTL on SSC5 had Mendelian mode of gene action (Table 2).
QTL models with parent-of-origin effect have been implemented to identify genes that have gene expression patterns in non-Mendelian patterns.
parent-of-origin or Mendelian QTL was performed according to the decision trees in Thomsen et al.