parakeratosis

parakeratosis /para·ker·a·to·sis/ (-ker″ah-to´sis) persistence of the nuclei of keratinocytes as they rise into the stratum corneum of the epidermis. It is normal in the epithelium of the true mucous membrane of the mouth and vagina.

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par·a·ker·a·to·sis (pr-kr-tss)

n.

Retention of nuclei in the cells of the stratum corneum of the epidermis, as in psoriasis.

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parakeratosis

[-ker′ətō′sis]

an abnormal formation of horn cells of the epidermis caused by the persistence of nuclei, incomplete formation of keratin, and moistness and swelling of the horn cells. It is observed as scaling in many conditions such as psoriasis.

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parakeratosis (per´kertō´sis),

n the persistence of nuclei in the stratum corneum keratin layer of stratified squamous epithelium. Associated with the masticatory mucosa of the attached gingiva; may be an immature form of orthokeratinized epithelium.

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parakeratosis

persistence of the nuclei of keratinocytes as they rise into the horny layer of the skin; it occurs normally in the epithelium of the true mucous membrane of the mouth and vagina. When it occurs on the external skin it constitutes a lesion. The appearance is of thickening of the skin with thick scale formation, cracking and fissuring, and an underlying raw red surface. Occurs as a specific disease in pigs fed on rations deficient in zinc; the effect is exacerbated on diets high in calcium.

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inherited parakeratosis

occurs in calves, which are normal at birth but develop parakeratosis all over the body, especially on the legs and die after a long illness. Responds to treatment with zinc given orally. See also thymic hypoplasia. Called also lethal trait A46, adema disease.

ruminal parakeratosis

the ruminal papillae are enlarged, leathery and adhered in clumps. The lesion is most severe in the dorsal part of the sac. Occurs principally in animals fed pelleted feed.