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papaverine hydrochloride

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papaverine hydrochloride
[papav′ərēn]
a vasodilator.
indications It is prescribed in the treatment of cardiovascular or visceral spasms.
contraindications Known hypersensitivity to this drug prohibits its use, and it must be used with caution in patients with glaucoma. It must be administered slowly because it can cause apnea and arrhythmias. Larger dosages can cause AV block.
adverse effects The most serious adverse effects include jaundice, tachycardia, arrhythmias, drowsiness, headache, weakness, nausea, and vomiting.


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Papaverine hydrochloride is relatively unstable in nonacidic solutions and a white precipitate sometimes forms when papaverine is added to plasmalyte solution (pH=7.
Drugs such as papaverine hydrochloride, phentolamine, and alprostadil (marketed as Caverject) widen blood vessels.
Drugs such as papaverine hydrochloride, phentolamine, and prostaglandin E1 widen blood vessels.
 
 
 
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