yellow fat disease

A vitamin E deficiency syndrome affecting various mammals, in particular cats, who are fed excess omega-3 polyunsaturated fatty acids from fish oils, especially tuna.

Clinical findings
Greasy, dull coat and flaky skin; severe pain when touched; anorexia, fever. In humans, excess fish-oils cause increased bleeding time, especially after aspirin ingestion, which may play a role in cardiac necrosis and increased susceptibility to catecholamine-induced stress.

Limit intake of tuna; add vitamin E to diet.


1. inflammation of body fat.
2. a disease of cats and aquarium fish fed on a diet high in polyunsaturated fats and low in vitamin E. In cats there is inflammation of all fat tissues; in fish there is also thickening of the swim bladder. See also yellow fat disease.
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References in periodicals archive ?
Nutritional fat necrosis (ie, pansteatitis or "yellow fat disease") has been reported in avian species.
Vitamin E deficiency and pansteatitis in juvenile boat-billed herons (Cochlearius cochlearius).
Feline pansteatitis revisited: hazards of unbalanced home-made diets.
Pansteatitis (steatitis, "yellow fat disease") in the cat: a review article and report of four spontaneous cases.
It is known they are dying of pansteatitis from a lack of vitamin E.
I have changed their diet recently, almost eliminating fish, after reading an article by a vet about pansteatitis.