pancreatic endocrine tumor

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A neoplasm of the endocrine pancreas–eg, Apudoma, islet cell tumor, nesidioblastoma, common in the body and tail, the sites of ↑ concentration of islets of Langerhans; PETs are seen in 0.5-1.0% of unselected autopsies, hormonally active tumors comprise < 1:105; PET names reflect the predominant hormone–eg, gastrinoma, glucagonoma, VIPoma, PPoma etc, although most PETs produce ≥ 1 hormone Prognosis Most PETs are indolent with a 10-yr survival post-resection; aggressive PETs may need chemotherapy, streptozocin. See Endocrine pancreas, WDHA syndrome, Zollinger-Ellison syndrome.

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