There is no known association between elevated CA 19-9 levels and pancreas divisum, but pancreas divisum has been associated with pancreatitis.
Possible causes include irritation of the pancreas by duodenal ulceration, or pancreatitis associated with the patient's variant of pancreas divisum.
A multicenter, double-blind, placebo-controlled clinical trial evaluated SecreFlo(TM) in patients with pancreas divisum
and established that 89% of patients who received SecreFlo(TM) prior to ERCP were successfully cannulated versus a 6% success rate in patients who received a placebo (p<0.
MRI is typically performed for evaluation of etiologies, such as gallstones or pancreas divisum
Resection for pancreatitis in patients with pancreas divisum
The etiology for disease included alcohol (n = 15), hereditary (n = 5), idiopathic (n = 6), pancreas divisum
(n = 3), stricture (n = 2), trauma (n = 2), systemic lupus erythematosus (n = 1), and unknown (n = 10).
Others cases result from pancreatic neoplasms, pancreas divisum
, cystic fibrosis, hyperparathyroidism, or hereditary pancreatitis.