pamidronate

pamidronate

 [pam″ĭdro´nāt]
an inhibitor of bone resorption, used to treat malignancy-associated hypercalcemia, Paget's disease of bone, and osteolytic metastasis secondary to breast cancer or myeloma; used as the disodium salt. Complexed with technetium 99m it is used in bone imaging.

pamidronate

/pam·i·dro·nate/ (pam″ĭ-dro´nāt) an inhibitor of bone resorption used to treat malignancy-associated hypercalcemia, osteitis deformans, and osteolytic metastasis secondary to breast cancer or myeloma; used as the disodium salt. Complexed with technetium 99m, it is used in bone imaging.

pamidronate

Aredia® Metabolism A 2nd-generation biphosphonate used to manage osteoporosis and Paget's disease of bone. See Biphosphonate, Osteoporosis.

pamidronate

A BISPHOSPHONATE drug that prevents bone reabsorption by interfering with the action of osteoclasts. The drug has been used to treat cancer bone metastases and MULTIPLE MYELOMA. A brand name is Aredia.
References in periodicals archive ?
Contract award: drugs group m - preparations acting on the musculoskeletal system - pamidronate.
In one study, pamidronate resulted in a significant reduction of pain in three patients with hypertrophic osteoarthropathies.
Zoledronic acid is superior to pamidronate in the treatment of hypercalcemia of malignancy: a pooled analysis of two randomized, controlled clinical trials.
Special newly designed rods fitted to her femur and tibia provide some protection, and new medications, such as pamidronate, help with pain and minimize breaks.
16) A Toulouse grey goose (Anser anser domesticus) was treated with carboplatin and pamidronate after unsuccessful treatment with radiation therapy.
Exposure to pamidronate has been described to cause a characteristic collapsing variety of FSGS (2).
5 L/Kg Bortezomib small 384 83 >500 L amount Pamidronate 20-55 235 54 0.
Studies evaluating the effects of pamidronate and zoledronate on skeletal metastases of thyroid cancer have been reported Rosen et al.
The efficacy of clodronate, pamidronate, and zoledronate in preventing bone lesions has been investigated in several randomised trials, while for ibandronate limited data from randomised trials are available (32).
To date, alendronate, pamidronate, and zoledronate seem to be effective in increasing BMD and normalizing bone turnover (3,5,16).
Pamidronate (Aredia), combination thiosulfate/abatacept, and diltiazem have produced excellent responses in children, but clinicians must be realistic about the response rates in adults, she added.