palmar-plantar erythrodysesthesia syndrome

palmar-plantar erythrodysesthesia syndrome

a side effect of some chemotherapy drugs caused by capillary leakage of the drug into tissues, particularly the hands and feet in humans and the paws or feet in animals. Tissue damage results in redness, swelling and blisters. Tingling or burning is reported in humans.
References in periodicals archive ?
20 April 2011 - Spanish biopharmaceutical company Advancell has announced the initiation of a clinical Phase IIb study of its treatment ATH008 for palmar-plantar erythrodysesthesia syndrome, or hand-foot syndrome, a painful side effect of chemotherapy.