palmar-plantar erythrodysesthesia


Also found in: Acronyms.

palmar-plantar erythrodysesthesia

A toxic effect of chemotherapy, characterized by burning or tingling discomfort in the hands and the soles of the feet occurring after the administration of cancer chemotherapy. Red, violet, and swollen skin may develop on the hands and feet and may shed, crust, or ulcerate. Additional cycles of chemotherapy worsen the effect.