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pain modulation

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pain modulation
Neurology An ↑ or ↓ of the sensation of pain, possibly due to a 2º neural pathway. See Opioid-mediated analgesia system.


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The repeated application of laser may reduce tonic peripheral nociceptive afferent input to the dorsal horn and facilitate reorganisation of synaptic connections in the central nervous system producing pain modulation (Coderre et al 1993, Mense 1993).
MECHANISM OF ACTION Giordano's recent review of pain modulatory mechanisms described the involvement of several systems, including, but not limited to, intraspinal-segmental pain modulation, bulbospinal pain modulation, centrifugal pain modulation involving midbrain and descending inhibitory controls, opioid and nonopioid hypothalamicpituitary analgesia, and corticolimbic inhibitory processing [147].
Pain modulation and opiate binding sites share the same neural structures and pathways.
 
 
 
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