pachyonychia congenita

pachyonychia /pachy·onych·ia/ (pak″e-o-nik´e-ah) abnormal thickening of the nails.

---

pachyonychia conge´nita  a rare, congenital, dominantly inherited disorder marked by great thickening of the nails, hyperkeratosis of palms and soles, and leukoplakia.

---

pachyonychia con·gen·i·ta (kn-jn-t)

n.

A hereditary syndrome marked by abnormal thickness and elevation of the nail plates, palmar and plantar hyperkeratosis, and a whitish and glazed tongue due to papillary atrophy. Also called Jadassohn-Lewandowsky syndrome.

---

pachyonychia congenita

Etymology: Gk, pachy + onyx, nail; L, congenitus, born with

a congenital deformity characterized by abnormal thickening and raising of the nails on the fingers and the toes and hyperkeratosis of the palms of the hands and the soles of the feet. The papillae of the tongue also atrophy, causing a whitish coating over the lingual surface.

---

pachyonychia [pak″e-o-nik´e-ah]

abnormal thickening of the nails.

pachyonychia conge´nita a congenital autosomal dominant syndrome primarily affecting males, characterized by increased thickness of the nails, hyperkeratosis involving the palms, soles, knees, and elbows, widespread tiny cutaneous horns, leukoplakia of the mucous membranes, and usually excessive sweating of the hands and feet; sometimes associated with development of bullae on palms and soles after trauma.