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p24 antigen

   Also found in: Wikipedia 0.01 sec.
p24 antigen
AIDS The 24 kD core antigen of HIV-1, which is linked to clinical AIDS; p24 is the earliest marker of HIV-1 infection, and detectable days to wks before seroconversion to anti-HIV-1 antibody production, detected by ELISA. Cf CD4:CD8 ratio, HIV, HIV RNA, Reverse transcriptase, Western blot.


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A decrease in protein S levels did not correlate with CD4+ cell count, CDC class, p24 antigen positivity, zidovudine use, or Pneumocystis carii prophylaxis, but a linear correlation was seen with duration of HIV infection.
It was shown to inhibit HIV-1 replication by inhibition of HIV-1 p24 antigen production in a dose-dependent manner.
During this period, HIV antibody and HIV p24 antigen tests were used to screen all blood donations in the country.
 
 
 
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