Also found in: Dictionary, Thesaurus, Encyclopedia, Wikipedia.
1. a bodily disturbance resulting from breathing high partial pressures of oxygen; characterized by visual and hearing abnormalities, unusual fatigue while breathing, muscular twitching, anxiety, confusion, incoordination, and convulsions; can occur when excessive quantities of oxygen are administered in patients (such as during adult respiratory distress syndrome), resulting in worsening of pulmonary infiltrates and clinical deterioration; although the mechanism for development of the condition is obscure, a disruption of enzymatic activity is likely, perhaps as a result of free radical formation. Compare: retrolental fibroplasia.
2. exposure of the lungs to greater than 60% oxygen for periods exceeding 24-48 hours can lead to severe, irreversible pulmonary fibrosis.
Synonym(s): oxygen poisoning
a condition of oxygen overdosage that can result in pathological tissue changes, such as retinopathy of prematurity or bronchopulmonary dysplasia. It can also decrease the hypoxic drive to breathe.
Pulmonary medicine Tissue and molecular damage due to the effects of O2 free radicals in cellular and extracellular micro-environments; OT occurs in infants—retinopathy of prematurity—and in the elderly—shock and inflammation
oxygen toxicityTissue and molecular damage due to the effects of O2 free radicals in cellular and extracellular micro-environments; OT occurs in older subjects, shock and inflammation. See Oxygen radical.
ox·y·gen tox·ic·i·ty(ok'si-jĕn tok-sis'i-tē)
A body disturbance resulting from breathing high partial pressures of oxygen; characterized by visual and hearing abnormalities, unusual fatigue while breathing, muscular twitching, anxiety, confusion, incoordination, and convulsions.
a chemical element, atomic number 8, atomic weight 15.999, symbol O. See Table 6. It is a colorless and odorless gas that makes up about 20% of the atmosphere. In combination with hydrogen, it forms water; by weight, 90% of water is oxygen. It is the most abundant of all the elements of nature. Large quantities of it are distributed throughout the solid matter of the earth, because the gas combines readily with many other elements. With carbon and hydrogen, oxygen forms the chemical basis of much organic material. Oxygen is essential in sustaining all kinds of life.
an instrument that measures the concentration of oxygen in a gas mixture.
significant cause of losses in cultivated finfish in enclosed dams, but also in rivers and estuaries, caused by lack of natural aeration of the water or to heavy algal blooms, bushfire ash deposits and overcast conditions leading to respiration rather than photosynthesis or a high concentration of organic matter and leading to the development of a bacterial bloom; a high temperature exacerbates the development.
oxygen flux equation
a calculation that determines the rate at which oxygen is made available to tissues, based on cardiac output and arterial oxygen content.
oxygen-hemoglobin dissociation curve
a graphic explanation of the release and acquisition of oxygen from and to the hemoglobin in the blood in varying circumstances of oxygen partial pressure in the environment.
see reducing valve.
the amount of oxygen bound to hemoglobin in the blood expressed as a percentage of the maximal binding capacity.
oxygen saturation curve
graphical representation describing the relationship (usually curvilinear) between fraction of oxygen-binding sites (of a protein) that have oxygen bound to them and the partial pressure (concentration) of free oxygen.
the heavy metal cylinder in which medical gases are compressed at high pressure. Called also oxygen cylinder.
see tension (2).
an enclosed space or plastic canopy used for oxygen therapy, humidity therapy or aerosol therapy.
supplemental oxygen administered for the purpose of relieving hypoxemia and preventing damage to the tissue cells as a result of oxygen lack (hypoxia). Companion animals are usually placed in a special cage with oxygen piped to it. A mask is used for short-term administration. Large animals can be supplied by a nasal tube taped in place to deliver oxygen into the pharynx.
tissue damage may occur with exposure to high concentrations of oxygen for long periods. See also retrolental fibroplasia.
a functional chain describing the transfer of oxygen from the external environment to the metabolizing tissue; includes uptake in the respiratory system, binding to hemoglobin, transport through the circulatory system, diffusion and dissociation in tissues and utilization in mitochondria, i.e. oxidatable substrates and enzymes.
process of transfer of oxygen around the body either attached to hemoglobin or myoglobin.