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oxygen dissociation curve |
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oxygen dissociation curve
Oxygen saturation curve Physiology A curve that describes the relationship between Hb O2 saturation and tension; defined by a sigmoid curve which reflects the interaction of the 4 Hb molecules involved in
O2 uptake, transport and release; a 'right shift' of the curve indicates ↓ Hb affinity for O2, as occurs in ↓ pH–ie, acidosis, ↑ temperature, ↑ PCO2, while a 'left
shift' indicates ↑ O2 affinity with ↑ pH, ↓ temperature, ↓ 2,3 DPG and ↓ PCO2 Right shifts Acidosis, hyperthermia, alveolar hypoventilation, anemia Left shifts Alkalosis, hypothermia,
hyperventilation, carboxyhemoglobinemia, hypophosphatemia, ↑ fetal Hb. See 2,3 DPG. Want to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit the webmaster's page for free fun content. |
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