oxazolidinones

ox·a·zo·lid·i·nones

(oks'ă-zō-lid'i-nōnz)
Any of a new class of antibacterial antibiotics.

oxazolidinones

Antibiotic drugs used to treat infections for which commoner antibiotics are unsuitable or ineffective. An example is linezolid (Zyvox).
References in periodicals archive ?
Graber, "Substituent Effects on the Antibacterial Activity of Nitrogen-Carbon-Linked (Azolylphenyl) oxazolidinones with Expanded Activity Against the Fastidious Gram-Negative Organisms Hemophilous influenzae and Moraxella c atarrhalis" Journal of medicinal chemistry 43, 5 (2000): 953-970.
9,10) Although the mechanism of action is similar to other oxazolidinones, tedizolid has shown more advantages, as lower adverse effects over short courses of therapy and favorable pharmacokinetics.
Staphylococcus 390 Vancomycin, Mupirocin, Neomycin, Tetracycline, Chloramphenicol, Streptomycin, Spectinomycin, Macrolide, Lincosamide, Streptogramin A and B, Fosfomycin, Pleuromutilin, Trimethoprim, Apramycin, Phenicols, Oxazolidinones, Erythromycin, Gentamicin, Apramycin, Methicillin, Bleomycin, Antiseptic, Isoleucine, Pleuromutilins, Kanamycin, Trimethoprim, Minocycline and Penicillins.
aureus isolate(s) from each positive nasal swab were tested for susceptibility to the following 12 classes of antibiotics: aminoglycosides, beta-lactams, cephalosporins, fluoroquinolones, lincosamides, macrolides, oxazolidinones, rifamycin, streptogramins, sulfonamide, nitrofuran, and tetracyclines (see Table S1).
Moreover, new oxazolidinones, a class of drug effective against many NTMs, are currently being developed for TB and might prove clinically useful (17).
While tedizolid phosphate (SIVEXTRO[R]) belongs to the class of Oxazolidinones, oritavancin (ORBACTIV[TM]) and dalbavancin (DALVANCE[R]) are both lipoglycopeptides.
The answers might well be BANANANAMES (+67) like KERATINIZES, LEGITIMATIZES (both +79) and OXAZOLIDINONES (-36).
The oxazolidinones are a novel group of antimicrobials15.
aureus is resistant to major drugs like methicillin, vancomycin, and oxazolidinones.
Indeed, there have been a handful of new antibiotics that have been developed over the past decade, such as the lipopeptides (daptomycin), glycylcyclines (tigecycline), oxazolidinones (linezolid) and streptogramins (quinupristin/dalfopristin).