All tested antibiotics, clindamycin (CL1), erythromycin (ERY), gentamicin (GEN), levofloxacin (LVX), oxacillin
(OXA), were from SigmaAldrich (Milan, Italy).
Resistance test to Oxacillin
was performed to examine if Staphylococcus aureus is MRSA or not.
Determination of methicillin resistance in CoNS can be overestimated by phenotypic methods; therefore CLSI recommend detection of mecA in CoNS as the definitive test in serious infections and advise that oxacillin
testing in S.
The ability of bacteria to quickly become resistant to antibiotics has caused both increasing prescription doses of standard antibiotics, like methicillin and oxacillin
, as well as the need for development of new antibiotics, both of which increase toxicity, to continue to fight these resistant bacterial infections.
Selective agents such as methicillin, oxacillin
, or cefoxitin are typically added to a 6.
Common MRSA otorrhea culture results from all three patients in this series Resistance Sensitivity amoxicillin/clavulanate gentamicin cefazolin linezolid ciprofloxacin * tetracycline clindamycin TMP/SMX erythromycin vancomycin levofloxacin oxacillin
penicillin * Not reported for Patient 3.
Methicillin resistance was tested on the oxacillin
(6 [micro]g/ ml, Ranbaxy Private Limited) screen plate (with 4% NaCl) (20) using S.
aureus with methicillin (5 [micro]g) and oxacillin
Our strain was susceptible to lincomycin, clindamycin, erythromycin, tylosin, tetracycline, penicillin, neomycin, oxacillin
, gentamicin, trimethoprim sulphonamides, ceftiofur, and amoxicillin clavulanic acid but was resistant to enrofloxacin.
1 MRSA Oxacillin
Linezolid Recovered (sputum) Erythromycin Levofloxacin 2 MRSA Oxacillin
Ciprofloxacin Recovered (sputum) Erythromycin plus Pseudomonas Ciprofloxacin clindamycin aeruginosa (sputum) 3 MRSA Oxacillin
Vancomycin Died (sputum) (rash), then Pseudomonas tigecycline aeruginosa plus aztreonoam 4 MRSA Oxacillin
Vancomycin Improved, (sputum) then hospice care 5 MRSA Oxacillin
Linezolid Died (sputum) Levofloxacin 6 MRSA Oxacillin
Vancomycin Recovered (sputum) Levofloxacin Clindamycin
Neisseria gonorrhoeae, and streptococci, and for testing staphylococci for potential methicillin or oxacillin
These antibiotics include methicillin and other more common antibiotics such as oxacillin
, penicillin and amoxicillin.