overflow proteinuria


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proteinuria

 [pro″te-nu´re-ah]
an excess of serum proteins in the urine, such as in renal disease, after strenuous exercise, or in dehydration.
accidental proteinuria (adventitious proteinuria) proteinuria due not to a kidney disease but to some other condition such as hemorrhage in the urinary tract; called also false proteinuria.
athletic proteinuria effort proteinuria.
dietetic proteinuria (digestive proteinuria) functional proteinuria produced by the eating of certain foods.
effort proteinuria functional proteinuria occurring as a result of vigorous and prolonged exercise of the lower limbs; called also athletic proteinuria.
false proteinuria adventitious proteinuria.
functional proteinuria any proteinuria that is not due to renal disease, such as the transient proteinuria of pregnancy, effort proteinuria, and orthostatic proteinuria.
glomerular proteinuria the most common kind of proteinuria, being due to glomerular disease and abnormal permeability of the glomerular capillaries to protein.
orthostatic proteinuria a form of functional proteinuria, usually seen between the ages of ten and twenty, that occurs on standing erect and disappears on lying down.
overflow proteinuria that due to hemoglobin, myoglobin, or immunoglobulin loss into the urine due to excessive amounts in the bloodstream, such as in multiple myeloma; it is not usually associated with glomerular or tubular disease.
tubular proteinuria proteinuria due to excretion of proteins of low molecular weight such as immunoglobulins, which normally should be reabsorbed.

overflow proteinuria

Persistent proteinuria without glomerular disease, with excess production of filterable, low-molecular-weight proteins, exceeding resorptive capacities of the renal tubules–eg, ↑ lysozyme in myelomonocytic–M4 leukemia or Bence-Jones proteinuria; OP is usually asymptomatic if the protein loss is < 2.0 g/day

overflow proteinuria

Release of proteins into the urine because of saturation of the normal reabsorbing capacity of the proximal tubules. It is found in conditions such as multiple myeloma and rhabdomyolysis.
See also: proteinuria