In a study in 1388 by Soleimani et Mehranjani diabetic mice was performed on a total volume of ovarian cortex
and medulla increased significantly in the diabetic group than in the other groups , which results We are in agreement.
Infertility treatments available for POI which may be used before or during ovarian failure, especially in cancer patients, include fertility preservation such as ovarian cortex
, oocyte and embryo cryopreservation, oocyte or embryo donation and adoption in women without any ovarian function (1).
Unlike the freezing of oocytes or embryos to preserve potential fertility, which requires ovarian stimulation, the ovarian cortex
can be harvested from a cancer patient without delay, permitting immediate initiation of chemotherapy and/or radiation therapy.
They found injury to blood vessels and focal fibrosis of the ovarian cortex
in ovaries of patients previously exposed to chemotherapy.
For women without a partner for sperm donation, oocyte cryopreservation  or ovarian cortex
or, indeed, whole ovarian tissue can be considered.
This study shows that transplantation of just six pieces of frozen/thawed ovarian cortex
to a woman who experienced chemotherapy-induced menopause can result in the production of fully mature oocytes for a period exceeding four years and that the capacity to sustain embryogenesis and give birth to healthy children remains," the research team, led by Dr.
The idea of cryopreserving ovarian tissue is based on the finding that the ovarian cortex
harbors primordial follicles that are more resistant to cryo-injury than are mature oocytes.
Ariel Revel and colleagues note that ovarian cortex
preservation is now routine for prepubertal girls at many cancer centers, but future use of this tissue may be limited.
After the aspiration, the ovarian cortex
of 1 mm in thickness were separated from the whole tissue and the cortex was subsequently cut into 2-5 [mm.
Before the woman received chemotherapy in 1997 and 1998, five biopsy strips of ovarian cortex
were taken from her left ovary, each about 12-15 mm long and 5 mm wide.
Microscopically, the reddish nodule consisted of a small, nonencapsulated, well-defined sinusoidal and vascular lesion within the ovarian cortex
that did not compress the adjacent ovarian tissue (Figure 1).
Dr Ariel Revel said: "The possibility of preserving the ovarian cortex
prior to surgery, drug or radiotherapy treatment offers new hope for young cancer patients.