ouabain


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oua·ba·in

(wah-bin, wah'bah-in),
A glycoside and African arrow poison from ouabaio, obtained from the wood of Acocanthera ouabaio or from the seeds of Strophanthus gratus; its action is qualitatively identical to that of strophanthus and the digitalis glycosides; used for rapid digitalization; often used in pharmacologic studies because of water solubility.

ouabain

(wä-bā′ĭn)
n.
A white poisonous glycoside, C29H44O12, extracted from the seeds of certain African trees of the genera Strophanthus and Acokanthera, that is used as a dart poison in some parts of Africa and has been used to treat congestive heart failure.

ouabain

(wă-bā′ĭn)
A glycoside prepared from Strophanthus gratus. Its action is similar to that of digitalis.

ouabain

a cardiac glycoside obtained chiefly from the plant Strophanthus gratus; its effect is similar to that of digitalis, but digitalization is achieved more rapidly.
References in periodicals archive ?
htm) American Chemical Society , which publishes the journal, explained that at low levels ouabain is used to regulate blood pressure or treat cardiac patients, but in higher doses can damage the heart.
Spinal antinociceptive action of Na+-K+ pump inhibitor ouabain and its interaction with morphine and lidocaine in rats.
Ruthenium-red inhibits CGRP release by capsaicin and resiniferatoxin but not by ouabain, bradykinin or nicotine in guinea-pig heart: correlation with effects on cardiac contractility.
To test this premise, we investigated the proapoptotic actions of digoxin, ouabain, and DLIF in a human acute T-cell lymphoblastic leukemic cell line (Jurkat E6-1), a human myelogenous erythroblastoid leukemic cell line (K-562), and peripheral blood mononuclear cells (PBMCs) isolated from healthy volunteers.
Schoner, Ouabain, a new steroid hormone of adrenal gland and hypothalamus.
w *one chiHUaHUa mariJUana choir OUabain sUite We hoWE WHat poWWow y onIon bouILLon halleluJah carilLon tortiLLa cogNac manana tenUre Yes intagl*i
We hypothesize that modifying the arginine will increase ouabain binding to the rat red blood cell.
This piece detailed the surprising finding that the human body apparently makes ouabain -- a hormone first found in plants -- and that the compound may cause some cases of hypertension and perhaps play a role in heart disease as well.
Hydrochlorothiazide (HCTZ; thiazide diuretic), acetazolamide (ACTZ; carbonic anhydrase inhibitor), ouabain octahydrate (sodium potassium ATPase inhibitor), N-[omega]-Nitro-L-arginine methyl ester (L-NAME; NO synthase inhibitor), icatibant acetate (HOE-140; [B.
ATPase subunit genes are up-regulated during the morula to blastocyst transition, (c) treatment with ouabain (a potent and specific inhibitor of the [Na.