ouabain


Also found in: Dictionary, Thesaurus, Encyclopedia, Wikipedia.

oua·ba·in

(wah-bin, wah'bah-in),
A glycoside and African arrow poison from ouabaio, obtained from the wood of Acocanthera ouabaio or from the seeds of Strophanthus gratus; its action is qualitatively identical to that of strophanthus and the digitalis glycosides; used for rapid digitalization; often used in pharmacologic studies because of water solubility.

ouabain

(wä-bā′ĭn)
n.
A white poisonous glycoside, C29H44O12, extracted from the seeds of certain African trees of the genera Strophanthus and Acokanthera, that is used as a dart poison in some parts of Africa and has been used to treat congestive heart failure.

ouabain

(wă-bā′ĭn)
A glycoside prepared from Strophanthus gratus. Its action is similar to that of digitalis.

ouabain

a cardiac glycoside obtained chiefly from the plant Strophanthus gratus; its effect is similar to that of digitalis, but digitalization is achieved more rapidly.
References in periodicals archive ?
Ouabain targets mainly on the small vessels and the myocardial cell, rather than on the large vessels, and therefore can be useful to distinguish between relevant obstructive coronary atherosclerosis and the actual ischemia in the microvasculature or in the myocardial cell itself.
It was well known that ouabain is a widely used agent to screen and evaluate antiarrhythmic drugs all over the world.
adrenals, where ouabain is made) nourish the heart.
The Crested Rat appears to be completely immune to ouabain, which is well known for its heart-arresting properties.
These observations are attributed to associations of the Trp460 allele with increased Na+/K+-ATPase activity and renal tubular sodium reabsorption as well as elevated levels of plasma ouabain, a natriuretic hormone that has vasoconstrictive properties (5, 6, 26).
The GTPase activity was reduced in the W07-toxin treated mice enterocytes which was found to be increased in presence of ouabain, a non-specific inhibitor of GTPase.
Ouabain inhibition of gill Na-K-ATPase: relationship to active chloride transport.
Ouabain binding and potassium transport in young and old populations of human red cells.
To test this premise, we investigated the proapoptotic actions of digoxin, ouabain, and DLIF in a human acute T-cell lymphoblastic leukemic cell line (Jurkat E6-1), a human myelogenous erythroblastoid leukemic cell line (K-562), and peripheral blood mononuclear cells (PBMCs) isolated from healthy volunteers.
w *one chiHUaHUa mariJUana choir OUabain sUite We hoWE WHat poWWow y onIon bouILLon halleluJah carilLon tortiLLa cogNac manana tenUre Yes intagl*i