ototoxic drug

ototoxic drug

ENT A drug that can damage the hearing and vestibular/balance organs of the inner ear
References in periodicals archive ?
OPI is a development-stage biopharmaceutical company committed to developing and commercializing novel pharmacological solutions and approaches to treat hearing disorders, including acute sensorineural hearing loss due to noise or ototoxic drug exposure, tinnitus, and the restoration of hearing by regeneration of cochlear hair cells.
The identification of relevant candidate compounds will be further developed as lead drug candidates in noise and ototoxic drug induced in vivo models.
The remainder are either infectious (with congenital cytomegalovirus infection being the leading culprit), caused by maternal ototoxic drug use during pregnancy, or idiopathic.
Birds exhibit the remarkable capacity to regenerate new hair cells, replacing those destroyed by ototraumatic events such as exposure to loud sound, ototoxic drug exposure, viral insults, etc.
The researchers worked with an ototoxic drug, called gentamycin, labeled with a red dye.
Bupropion is not considered an ototoxic drug," noted Dr.
In preclinical studies, ebselen treatment was shown to reduce the TTS and permanent threshold shift (PTS) caused by intense noise exposure or ototoxic drug exposure such as cancer chemotherapy.
The serious lack of audiological testing facilities, hearing aids and audiological rehabilitation in the Western Cape, is compromising MDR-TB care for patients who have become deaf as a consequence of ototoxic drug therapy.
However, hearing loss may not manifest until several weeks or months after completion of a course of an ototoxic drug.
Hearing loss acquired between adolescence and the age of 50 may be due to relatively uncommon causes, such as Meniere's disease, trauma, otosclerosis, ototoxic drug exposure, and eighth cranial nerve tumors.
All patients fulfilled the International Study Group's diagnostic criteria for Behcet disease (2) Patients with a history of recurrent otitis, cranial trauma, ototoxic drug use, any condition related to inner ear damage, and any otologic or neurologic disease unrelated to Behcet disease were excluded from the study.