osteoradionecrosis /os·teo·ra·dio·ne·cro·sis/ (-ra″de-o-nĕ-kro´sis) necrosis of bone as a result of exposure to radiation.
osteoradionecrosis (ORN) (os´tēōrā´dēōnekrō´sis),
osteoradionecrosis
os·te·o·ra·di·o·ne·cro·sis ( s t - -r d--n -kr s s)n. Necrosis of bone caused by exposure to ionizing radiation. |
osteoradionecrosis (ORN) (os´tēōrā´dēōnekrō´sis),
n bone necrosis secondary to irradiation and superimposed infection. It occurs because radiation inevitably destroys normal cells and blood vessels, as well as tumor cells. Damage to the small arteries reduces circulation to the area, depriving it of oxygen and other necessary nutrients. Sequestrum formation can be noted on the radiographs. Mainly treat with hyperbaric oxygen.
osteoradionecrosis
necrosis of bone as a result of excessive exposure to radiation.
osteoradionecrosis
Degenerative pathology caused by radiation-induced cell injury, resulting in ↓ cell repair, ↓ vascularity, local hypoxia, necrosis, defective wound healing Clinical Edema, ulceration, bone necrosis, poor wound
healing Management Hyperbaric O2. See Hyperbaric oxygen therapy.
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