osteodystrophy

osteodystrophy /os·teo·dys·tro·phy/ (-dis´trah-fe) abnormal development of bone.

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renal osteodystrophy  a condition due to chronic kidney disease and renal failure, with elevated serum phosphorus levels, low or normal serum calcium levels, and stimulation of parathyroid function, resulting in a variable admixture of bone disease.

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os·te·o·dys·tro·phy (st--dstr-f)

n.

Defective formation of bone. Also called osteodystrophia.

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osteodystrophy

[-dis′trəfē]

Etymology: Gk, osteon + dys, bad, trophe, nourishment

any generalized defect in bone development, usually associated with disturbances in calcium and phosphorus metabolism and renal insufficiency, such as in renal osteodystrophy. Also called osteodystrophia.

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osteodystrophy [os″te-o-dis´trŏ-fe]

abnormal development of bone.

renal osteodystrophy a condition due to chronic kidney disease and renal failure, marked by impaired vitamin D metabolism, elevated serum phosphorus levels, low or normal serum calcium levels, and stimulation of parathyroid function. There may be any of various bone diseases, including osteitis fibrosa cystica, osteomalacia, osteoporosis, and sometimes osteosclerosis. If onset is in childhood, renal dwarfism may result.

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osteodystrophy

diseases of bone in which there is failure of normal development or abnormal metabolism in bone which is already mature. Principal clinical signs are distortion and enlargement of bones, susceptibility to fracture, and abnormalities of gait and posture. See also osteodystrophia fibrosa.

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hypertrophic osteodystrophy

a disease of unknown etiology that occurs in young, rapidly growing dogs primarily of the large or giant breeds, in which there is pain and soft tissue swelling usually around the distal radius, ulna and tibia, lameness, and varying degrees of fever, lethargy and anorexia. Periosteal new bone is formed around the metaphyses and sometimes diaphyses, contributing to the enlargement of the limbs. The cause is unknown but hypovitaminosis C has at various times been suggested. Called also Möller-Barlow's disease (from a similar human disease), Barlow's disease, skeletal scurvy, infantile scurvy, osteodystrophy II, metaphyseal osteopathy, canine hypertrophic osteodystrophy.

renal osteodystrophy

see renal secondary hyperparathyroidism.

Hypertrophic osteodystrophy in a 4-month-old Great Dane. By permission from Lamb CR, Diagnostic Imaging of the Dog and Cat, Mosby, 1993

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osteodystrophy

Orthopedics A general term for defective development of bone. See Renal Osteodystrophy.