Osteoclast (redirected from osteoclastic)

osteoclast /os·teo·clast/ (os´te-o-klast?)

1. a large multinuclear cell associated with absorption and removal of bone.

2. an instrument used for osteoclasis.osteoclas´tic

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os·te·o·clast (st--klst)

n.

1. A large multinucleate cell found in growing bone that resorbs bony tissue, as in the formation of canals and cavities. Also called osteophage.

2. An instrument used in surgical osteoclasis.

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oste·o·clastic adj.

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Osteoclast

Cell that absorbs bone.

Mentioned in: Multiple Myeloma

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osteoclast (os´tēōklast),

n a large, multinucleated giant cell associated with the resorption of bone; the nuclei resemble the nuclei of the osteoblasts and osteocytes; the cytoplasm is often foamy, and the cell frequently has branching processes. They may arise from stromal cells of the bone marrow. They may represent fused osteoblasts or may include fused osteocytes liberated from resorbing bone. They are usually found in close relationship to the resorption of bone and frequently lie in areas of resorption (Howship's lacunae).

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osteoclast

1. a large, multinuclear cell frequently associated with resorption of bone.

2. a surgical instrument used for osteoclasis.

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osteoclast-activating factor (OAF)

a product of activated T lymphocytes that takes part in local resorption of bone.