the occurrence of multiple osteochondromas.
he·red·i·tar·y mul·ti·ple ex·os·to·ses[MIM*133700]
a disturbance of endochondral bone growth in which multiple, generally benign osteochondromas of long bones appear during childhood, commonly with shortening of the radius and fibula; the skull is not involved; the ill effects are usually mechanical but malignant change is rare; autosomal dominant inheritance with genetic heterogeneity. Type I is caused by a mutation in the exostosis-1 gene (EXT1) on 8q, type II is due to mutation in the exostosis-2 gene (EXT2) and type III maps to 19p.
osteochondromatosis/os·teo·chon·dro·ma·to·sis/ (-kon-dro″mah-to´sis) occurrence of multiple osteochondromas, sometimes specifically denoting one of the disorders multiple cartilaginous exostoses or enchondromatosis.
the transformation of synovial villi into bone and cartilage masses, causing loose bodies in the joints. It usually develops in joints affected by injury or degenerative disease.
the occurrence of multiple osteochondromas. See multiple cartilaginous exostosis.