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osmotic diuresis

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diuresis /di·ure·sis/ (di″u-re´sis) increased excretion of urine.
osmotic diuresis  that resulting from the presence of nonabsorbable or poorly absorbable, osmotically active substances in the renal tubules.
pressure diuresis  increased urinary excretion of water when arterial pressure increases, a compensatory mechanism to maintain blood pressure within the normal range.

osmotic diuresis,
diuresis resulting from the presence of certain nonabsorbable substances in tubules of the kidney, such as mannitol, urea, or glucose.

diuresis
increased excretion of the urine.

cold diuresis
occurs in hypothermia as a result of peripheral vasoconstriction, hyperglycemia and decreased renal tubular absorption.
osmotic diuresis
due to increased concentration of solutes which are not reabsorbed in the proximal tubules and which, by osmotic pressure, cause water to be retained. See also osmotic diuretic.
postobstruction diuresis
due to the diuretic effect of urea and electrolytes retained during the period of obstruction.
water diuresis
ingestion and excretion of an excess of water, without a corresponding amount of sodium; involves expansion of plasma volume, increased left atrial pressure and inhibition of ADH. See also obligatory water diuresis.


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Recovery from acute renal failure, postobstructive diuresis, and osmotic diuresis can all lead to renal potassium loss.
This is a classic presentation of an osmotic diuresis secondary to urea.
The decrease in the rate of NMC in diabetic patients could be due to a decrease in ATPase activity, poor stimulation (due to neuropathy), osmotic diuresis (with its loss of water and electrolytes), and altered carbohydrate metabolism.
 
 
 
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