orthotopic


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Related to orthotopic: Orthotopic Liver Transplantation, orthotopic neobladder

orthotopic

 [or″tho-top´ik]
1. occurring at the normal place in the body.
2. pertaining to a tissue transplant grafted into its normal place in the body.

or·tho·top·ic

(ōr'thō-top'ik),
In the normal or usual position.
[ortho- + G. topos, place]

orthotopic

/or·tho·top·ic/ (or″tho-top´ik) occurring at the normal place.

or·tho·top·ic

(ōr'thō-tō'pik)
In the normal or usual position.
[ortho- + G. topos, place]

orthotopic

occurring at the normal place.
References in periodicals archive ?
Intravenous urography and isotope renography show the function of the orthotopic kidney, but also the lack of function in the ipsilateral lower mass and contralateral flank.
Connective tissue growth factor specific antibody attenuates tumor growth, metastasis and angiogenesis in an orthotopic mouse model of pancreatic cancer.
2012 JVIR Editor's Award for Outstanding Laboratory Paper: "Intratumoral Versus Intravenous Gene Therapy Using a Transcriptionally Targeted Viral Vector in an Orthotopic Hepatocellular Carcinoma Rat Model.
1%, while in those with orthotopic bladder substitutions, recurrence rates are slightly lower at 0.
Material and methods: Between 2000 and 2008, out of 61 patients who underwent a Studer type orthotopic ileal neobladder construction following radical cystoprostatectomy, 18 patients who were regularly followed without local recurrence or distant metastases were enrolled in the study to evaluate the functional results and urodynamic characteristics of the neobladder.
Although GCH-AIHA association was reported more commonly among infants, there are rare reports of late-onset cases, such as in an 18-year-old male who survived after orthotopic liver transplantation (3).
The patient was a 54-year-old woman with a history of hypertension and dilated cardiomyopathy who underwent orthotopic heart transplantation on March 13, 2004.
Cryopreservation of Ovarian Tissue and the Whole Ovary: The first human live birth upon orthotopic transplantation of cryopreserved ovarian tissue was reported in 2004 (80), in spite of the introduction of the concept of ovarian transplantation since 1906 (81).
Furthermore, orthotopic tumor and disease models are increasingly preferred over less biologically relevant subcutaneous xenografts.
The company's liver transplant study will compare the efficacy, safety and tolerability of prophylactic use of CAMVIA versus oral ganciclovir when administered for up to 14 weeks for the prevention of cytomegalovirus (CMV) disease in recipients of orthotopic liver transplants at high risk for developing CMV disease.
Preliminary findings from the first randomized control trial of antiviral prophylaxis for the prevention of recurrent hepatitis C infection in orthotopic liver-transplant (OLT) patients suggest that although adverse events are common during prophylactic treatment with peg-interferon [alpha]-2a (Pegasys) plus ribavirin (Copegus), only a small percentage of those adverse events necessitate treatment withdrawal, Dr.