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orthotopic

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orthotopic /or·tho·top·ic/ (or″tho-top´ik) occurring at the normal place.
or·tho·top·ic (ôrth-tpk)
adj.
In the normal or usual position.

orthotopic [or″tho-top´ik]
1. occurring at the normal place in the body.
2. pertaining to a tissue transplant grafted into its normal place in the body.

orthotopic
occurring at the normal place.


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With an orthotopic ileal neobladder, daytime and nocturnal continence rates as high as 85% to 90% and 50% to 90%, respectively, can be achieved.
In addition, they assessed viability and apoptosis in ovarian cancer cell lines and tumour models and examined anti-tumour activity in orthotopic mouse models with mice bearing HeyA8-luc and SKOV3ip1 ovarian tumours.
There are currently several experimental ways of attempting this, the most direct of which, known as orthotopic grafting or autotransplantation, transfers the ovarian tissue back into the woman's body, near the site from which it was removed.
 
 
 
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