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orthologous genes

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orthologous genes
[ôrthol′əgəs]
genes in different species that are similar in their nucleotide sequences, suggesting that they originated from a common ancestral gene.


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Three criteria were followed to define the candidate orthologous genes suggested by [8] in the Ensemble web database.
We have also mined public DNA databases to obtain clam coding sequences and searched for intron positions by comparing these sequences with those of their putatively orthologous genes in model organisms.
Though the two ends of the mouse and human cluster are very similar, with orthologous genes in corresponding positions, the distinct organization in the middle of each cluster indicates that some major rearrangements have occurred since the two species diverged from a common ancestor.
 
 
 
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