ortholog


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Related to ortholog: paralog

ortholog

or

orthologue

(ôr′thə-lôg′, -lŏg′)
n.
A homologous gene that is related to those in different organisms by descent from the DNA of a common ancestor and that may or may not have the same function.

or·thol′o·gous (-thŏl′ə-gəs) adj.

ortholog

(ŏr′thō-lŏg″) [″ + (ana)log(ue)]
A gene that is shared by members of different species.
References in periodicals archive ?
Lepidoptera: Noctuidae) by identification of antimicrobial response orthologs (Terenius et al.
Selection of the Ortholog Table on the Reference Pathway page results in a list of organisms with the enzymes of the pathway.
The PathHunter[TM] -Arrestin Ortholog GPCR assays are fully validated, functional clonal cell lines expressing ortholog GPCRs that have been optimized to detect a full range of compound pharmacologies.
Identification of a protein ortholog for a known chemical molecular target can be used to infer possible effects, especially where an AOP exists.
To determine whether diosmetin could selectively inhibit MRSA PK without an effect on the human ortholog, 2 human isoforms, M1 and M2, were tested.
16,47,48) The functional defects of mutant Twinkle proteins have also been studied in the ortholog in Drosophila.
japonica were assessed using a publicly available ortholog sequence from the latter (Genbank accession no.
Zebrafish possess at least one unusually large family of putative immune genes, novel immune-type receptor genes (NITRs), for which a corresponding mammalian ortholog is not evident.
5) examined the cellular location of PLAC1 (the human ortholog of Plac1), and confirmed its placental expression throughout human pregnancy.
Phylogeny of Solanum series Piurana and related species in Solanum section Petota based on five conserved ortholog sequences.
Isolation and characterization of xnov, a Xenopus laevis ortholog of the chicken nov gene.
25) Deletion of chromosome 14 extending from the q24 to q31 band encompasses additional candidate genes involved in tumorigenesis, including SEL1L (the human ortholog of the C elegans sel-1 suppressor enhancer of lin-12), CHES1 (checkpoint suppressor 1), and MAP3K9 (mitogen activated protein kinase kinase kinase 9) genes.