and parakeratosis were seen, along with cellular debris in the cyst cavity.
Microscopically, the surface of the lesion displays hyperkeratosis and orthokeratosis
Histopathological studies showed inhibition in cellular infiltration and reduction of synovial hyperplasia and synovitis, whereas in the second test, histopathological and ultrastructural studies showed that topical application of FAM induced orthokeratosis with the presence of keratohyalin granules in the previously parakeratotic adult mouse tail, and without effects on epidermal thickness.
The induction of orthokeratosis in those parts of the adult mouse tail, which have normally a parakeratotic differentiation, was quantified measuring the length of the granular layer (A) and the length of the scale (B).
DA = [[mean OK of treated group - mean OK of control group]/[100 - mean OK of control group]] x 100 where OK = orthokeratosis.
Due to a non-gaussian distribution of orthokeratosis values (100% is the maximal effect) the Kruskal-Wallis test was used on psoriasis tail test.
FAM and retinoic acid induced a significant and dose-dependent increase in orthokeratosis in the mouse tail epidermis ([DE.
Suprabasilar clefts with acantholytic and dyskeratotic cells were located adjacent to and extending into the lumen of the cystic cavity; orthokeratosis and parakeratosis were present (Fig.
Acantholytic dyskeratosis is characterized by suprabasilar clefts, acantholysis and dyskeratosis within the epidermis, orthokeratosis, and parakeratosis.
Acantholytic dyskeratosis is characterized by the following changes within the epidermis: suprabasilar clefts, acantholysis, dyskeratosis, orthokeratosis, and parakeratosis.
In June 1998, a skin biopsy from both palms yeilded microscopic findings of compact orthokeratosis
with entrapped serum and transepidermal eliminated Langerhans' cell microabcesses (ie, small collections of Langerhans' cells), irregular epidermal hyperplasia, and a perivascular inflammatory infiltrate of lymphocytes, which were consistent with the diagnosis of dyshidrotic dermatitis.