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oropharyngeal cancer

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oropharyngeal cancer
ENT A malignancy of the lips, tongue, floor of mouth, salivary glands, buccal mucosa, gingiva, palate, and throat; most are SCCs linked to tobacco use and/or smoking, and tend to spread rapidly High risk factors Alcohol abuse, poor dental and oral hygiene, chronic irritation–eg, rough teeth, dentures, etc; OCs begin as leukoplakia or mouth ulcers; 2:1, ♂:♀. See Squamous cell carcinoma.
Oropharyngeal cancer-Stages
I   Lesion is ≤ 2 cm and confined to the oropharynx
II   Lesion is between 2 cm and 4 cm and confined to the oropharynx
III  Lesion is ≥ 4 cm and may involve a single lymph node on same side of neck
IV  Lesion has spread to the hard palate, tongue, or larynx, to nearby lymph nodes, or metastasized


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The largest and most definitive study to date has found that patients with stage III or IV oropharyngeal cancer (cancers of the upper throat) whose tumors contained the human papillomavirus (HPV) have better outcomes than patients with HPV-negative disease according to new research from the Radiation Therapy Oncology Group (RTOG).
Case-control study of human papillomavirus and oropharyngeal cancer.
 
 
 
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