oromandibular dystonia


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oromandibular dystonia

Neurology A condition that affects the muscles of the jaw, lips, and tongue; the jaw is either open or shut, and may be accompanied by dysphagia and/or dysphonia
References in periodicals archive ?
LN hyperechogenicity may not necessarily be a universal echo feature in patients with blepharospasm or oromandibular dystonia.
Hesham Abboud, Ilia Itin, and Hubert Fernandez, "Occupational Oromandibular Dystonia in an Opera Singer Mimicking Spasmodic Dysphonia," Music and Medicine 4, no.
Table 19: Incidence of EPS Compared to Placebo in the Adjunctive Therapy Bipolar Depression Studies Adverse Event Term Placebo LATUDA 20 to (N=334) 120 mg/day (%) (N=360)(%) All EPS events 13 24 Ail EPS events, 9 14 excluding Akathisia/Restlessness Akathisia 5 11 Dystonia* 1 1 Parkinsonism** 8 13 Restlessness 1 4 Note: Figures rounded to the nearest integer *Dystonia includes adverse event terms: dystonia, oculogyric crisis, oromandibular dystonia, tongue spasm, torticollis, and trismus **Parkinsonism includes adverse event terms: bradykinesia, cogwheel rigidity, drooling, extrapyramidal disorder, glabellar reflex abnormal, hypokinesia, muscle rigidity, parkinsonism, psychomotor retardation, and tremor
The terms oromandibular dystonia, craniocervical dystonia or Meige syndrome are often used to describe a focal or segmental dystonia whereby repetitive sustained spasms of the masticatory, facial, or lingual muscles result in involuntary, and possibly painful, jaw movements [3,4].
40] The effects of botulinum toxin in oromandibular dystonia are seen in 24 to 72 hours and generally last 10 weeks to 4 months.
Table 19: Incidence of EPS Compared to Placebo in the Adjunctive Therapy Bipolar Depression Studies Placebo LATUDA (N=334) 20 to 120 mg/day (%) (N=360) Adverse Event Term (%) All EPS events 13 24 All EPS events, excluding Akathisia/ 9 14 Restlessness Akathisia 5 11 Dystonia * <1 1 Parkinsonism ** 8 13 Restlessness <1 4 Note: Figures rounded to the nearest integer * Dystonia includes adverse event terms: dystonia, oculogyric crisis, oromandibular dystonia, tongue spasm, torticollis, and trismus ** Parkinsonism includes adverse event terms: bradykinesia, cogwheel rigidity, drooling, extrapyramidal disorder, glabellar reflex abnormal, hypokinesia, muscle rigidity, parkinsonism, psychomotor retardation, and tremor
Major Finding: A total of 10 patients with oromandibular dystonia experienced symptom relief after one treatment session with onabotulinumtoxinA injections; 10 required two sessions; and required more subsequent treatment.
Impact on quality of life of botulinum toxin treatments for spasmodic dysphonia and oromandibular dystonia.
dagger]) EPS includes bradykinesia, cogwhell rigidity, drooling, dystonia, extrapyramidal disorder, glabellar reflex abnormal, hypokinesia, muscle rigidity, oculogric crisis, oromandibular dystonia, parkinsonism, psychomotor retardation, tongue spasm, torticollis, tremor, and trismus.
Table 18: Incidence of EPS Compared to Placebo in the Monotherapy Bipolar Depression Study LATUDA 20 to 60 80 to 120 Placebo mg/day mg/day (N-168) (N=164) (N=167) Adverse Event Term (%) (%) (%) All EPS events 5 12 20 All EPS events, excluding 2 5 9 Akathisia/ Restlessness Akathisia 2 8 11 Dystonia * 0 0 2 Parkinsonism ** 2 5 8 Restlessness <1 0 3 Note: Figures rounded to the nearest integer * Dystonia includes adverse event terms: dystonia, oculogyric crisis, oromandibular dystonia, tongue spasm, torticollis, and trismus ** Parkinsonism includes adverse event terms: bradykinesia, cogwheel rigidity, drooling, extrapyramidal disorder, glabellar reflex abnormal, hypokinesia, muscle rigidity, parkinsonism, psychomotor retardation, and tremor
Patient distribution was as follows: Seven patients had chorea due to HD, 1 had tardive dystonia, 1 had oromandibular dystonia (OMD), 1 had post-ischemic hemidystonia, 1 had hemiballismus, and 1 patient had post-traumatic rubral tremor.
dagger]) EPS includes the following adverse events: bradykinesia, cogwheel rigidity, drooling, dystonia, extrapyramidal disorder, glabellar reflex abnormal, hypokinesia, muscle rigidity, oculogyric crisis, oromandibular dystonia, parkinsonism, psychomotor retardation, tongue spasm, torticollis, tremor, and trismus.