organophosphorus compound


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organophosphorus compound

an organic ester of phosphoric or thiophosphoric acid; such compounds are powerful acetylcholinesterase inhibitors and are used as insecticides and anthelmintics. They are also used industrially as fire-resistant hydraulic fluids, coolants and lubricants and animals may be accidentally exposed to them. All organophosphorus compounds are poisonous, even those used pharmacologically, if given in large enough doses or in particular circumstances.

organophosphorus compound-induced delayed neurotoxicity
paralysis occurring 3 weeks after exposure to organophosphorus compounds, especially industrial organophosphates; the degree of paralysis varies from weakness appearing as knuckling of the fetlocks to complete flaccid paralysis.
industrial organophosphorus compound
see organophosphorus compound (above). Includes aryl-, cresyl-, and tolyl- phosphates used commercially as flame retardants and wood preservatives. Access to the substances or, more commonly, premises contaminated by them may cause poisoning, especially delayed neurotoxicity.
organophosphorus compound insecticide
includes a very wide range of contact insecticides, systemic insecticides for animals and plants; all have significant toxic potential.
organophosphorus compound poisoning
signs of poisoning differ between the species. (1) Cattle show salivation and diarrhea, tremor and stiffness and a pathognomonic constriction of the pupil. (2) Sheep and pigs show predominantly nervous signs. In sheep ataxia, posterior paralysis and spinal cord degeneration are indicators. In pigs nystagmus, tremor, recumbency, posterior paralysis and drowsiness occur. (3) Horses show abdominal pain, diarrhea, ataxia, dyspnea and in foals acute bilateral laryngeal paralysis. (4) Dogs and cats show salivation, tremors and muscle fasciculations, vomiting and diarrhea, constriction of the pupils, ataxia and convulsions.
References in periodicals archive ?
Cross-Linked Enzyme Crystals of Organophosphate Hydrolase for Electrochemical Detection of Organophosphorus Compounds," World Journal of Microbiology and Biotechnology 24, no.
The concern about the negative impacts of organophosphorus compounds has led to alternative treatments.
It is likely that the cholinesterase depression detected in the blood samples was attributable solely to inhibition by the exposure to organophosphorus compounds as opposed to the carbamate pesticides.
Researchers at the institute first noticed differences in the way laboratory animals reacted to organophosphorus compounds.
Both insecticides and herbicides, most notably organochlorines, organophosphorus compounds, chlorophenoxy acids/esters, and botanicals, significantly increased the risk of Parkinson's disease.
THEORETICAL STUDY OF THE ADSORPTION OF ORGANOPHOSPHORUS COMPOUNDS ON METAL OXIDE SURFACES
Exposure to organophosphorus compounds, including the nerve agents satin and soman, can cause seizures, breathing difficulty, and death.
Pesticides are also classified by the chemical class to which they belong; they may be organochlorine compounds (OCs), organophosphorus compounds (OPs), carbamates, pyrethroids, phenoxy acids triazines, dinitroanilines, sulfonylureas, juvenile hormone analogs, insect growth regulators, microbial toxins, etc.
Savin (Russia): Savin is a Senior Researcher in the Organophosphorus compounds team, Institute of Organoelement Compounds, Russian Academy of Sciences.
In vitro effects of organophosphorus compounds on calmodulin activity.

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