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organification

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organification
[ôrgan′ifikā′shən]
a process in the thyroid gland whereby iodide is oxidized and incorporated into tyrosyl residues (tyrosine) of thyroglobulin. Organification is catalyzed by the enzyme thyroid peroxidase.
organification
conversion of glycoprotein in the thyroid gland resulting in the formation of thyroglobulin.
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5) Therefore, drugs that inhibit the organification process are not as successful in type II AIT, and glucocorticoids are more often used.
Pharmacodynamic effect of iopanoic acid on free [T.sub.3] and ... by Matrka, Laura; Steward, David; Falciglia, Mercedes; Nikiforov, Yuri / Ear, Nose and Throat Journal
Other causes are surgical removal of the thyroid gland, radioactive iodine thyroid gland ablation, external irradiation and a thyroid gland iodine organification defect.
Evaluation of thyroid dysfunction in patients with paroxysmal atrial ... by Vergara, Pasquale; Picardi, Giuseppe; Nigro, Gerardo; Scafuro, Francesco; de Chiara, Annabella; Cala / The Anatolian Journal of Cardiology (Anadolu Kardiyoloji Dergisi)
Maternal-fetal transfer of thyroxine in congenital hypothyroidism due to a total organification defect or thyroid agenesis.
Evaluation of the U.S. EPA/OSWER preliminary remediation goal for ... by Rice, Deborah C. / Environmental Health Perspectives
 
 
 
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