Dual-process action of exercise on appetite control: increase in orexigenic
drive but improvement in meal-induced satiety.
NPY has been shown to be a potent orexigenic
agent in chickens when administered centrally (Kuenzel and McMurtry, 1988).
It has been reported that heavy, continuous physical exercise compresses/reinforces orexigenic
(AgRP NPY, and ghrelin) and anorexigenic peptide/protein (obestatin, leptin, POMS, CART, and visfatin) secretion and its concentration in central and peripheral tissues (3-6).
Although there are many neuropeptides that stimulate food intake, ghrelin is the most established orexigenic
peptide known until now (21).
Ghrelin: more tan a natural GH secretagogue and/ora n orexigenic
sup] The orexigenic
peptides, HCRT-1 and HCRT-2 (HCRT, also known as orexin (OX)-A and OX-B), are proteolytically cleaved from a common precursor, prepro-OX, and share 46% amino acid sequence identity.
An interruption between the balance in anorexigenic and orexigenic
hormones may influence the progression of CKD-associated protein energy malnutrition in pediatric patients.
and anorexigenic peptides are the primary integrators of various nutritional information.
4] Because of its widespread distribution, ghrelin plays a pivotal role in a various physiological processes including orexigenic
regulation, neurohormonal control, energy and metabolic homeostasis, cardiovascular, immunological and other functions.
The Role of "Mixed" Orexigenic
and Anorexigenic Signals and Autoantibodies Reacting with Appetite Regulating Neuropeptides and Peptides of the Adipose Tissue-Gut-Brain Axis: Relevance to Food Intake and Nutritional Status in Patients with Anorexia Nervosa and Bulimia Nervosa.
Resistance to the orexigenic
effect of ghrelin in dietary-induced obesity in mice: reversal upon weight loss.
Ghrelin, one of the most potent orexigenic
hormones, has been suggested as another possible mediator of anorexia in ESRD patients.