oral hairy leukoplakia

(redirected from oral warts)

leukoplakia

 [loo″ko-pla´ke-ah]
a disease marked by the development of white thickened patches on the mucous membranes of the cheeks (leukoplakia buccalis), gums, or tongue (leukoplakia lingualis); the patches sometimes form fissures and often become malignant. They may grow into larger patches or form ulcers. Those in the mouth may in time cause pain during swallowing of food or speaking. Leukoplakia affects mostly middle-aged to elderly men, often after prolonged irritation of the mouth from such varying factors as badly fitting dentures or immoderate use of tobacco.

Treatment is aimed at removing any possible cause of physical or chemical irritation; the patient should give up tobacco and possibly also alcohol and extremely hot food. Dental attention may be necessary if teeth are uneven or dentures do not fit properly. Surgical removal of the affected area is relatively simple and may be the best means of preventing further development of the condition.
oral hairy leukoplakia a white filiform to flat patch occurring on the tongue or, rarely, on the buccal mucosa, caused by infection with Epstein-Barr virus and associated with human immunodeficiency virus infection.
leukoplakia vul´vae the presence of hypertrophic grayish-white infiltrated patches on the vulvar mucosa; specific diagnosis is determined by biopsy.

oral hairy leukoplakia

Enlarge picture
ORAL HAIRY LEUKOPLAKIA

oral hairy leukoplakia

Leukoplakia of the tongue. It is typically found in immunocompromised patients is a result of Epstein-Barr virus infection.
illustration
See also: leukoplakia

oral hairy leukoplakia (loo´kōplā´kēə),

n a filamentous, white plaque found on the lateral borders of the tongue that can spread across the entire dorsum of the tongue and onto the buccal mucosa. The Epstein-Barr virus (EBV) has been identified in biopsy specimens of these lesions. An indicator disease for AIDS. See also leukoplakia.
oral health diet score,
n a motivational aid to good nutrition. Merit points are earned by an adequate intake of foods from the recommended food groups. Demerits are given for frequent intake of foods high in sugars. The difference is the oral health diet score. The technique is applicable to children with a high incidence of dental caries.
oral health index,
n a statistical measure that quantifies one or more aspects of a person's or group's oral health status.
oral hygiene,
oral manifestation,
n the presence of the signs, symptoms, and lesions of a systemic disease in and around the oral cavity.
oral medicine,
oral mucosa,
oral physiology,
oral self-examination,
n the procedure shown to dental patients in order to look for indications of cancer. The patient monitors the tissues of his or her oral cavity, as well as those of the head and neck, reporting any changes to a dental professional.
oral surgery,
n See surgery, oral.
oral warts,
n.pl warts caused by human papillomavirus (HPV) that may be scattered throughout the oral cavity or localized in one area. They frequently recur. They are associated with AIDS infection.
References in periodicals archive ?
BULLETIN BOARD: AMAR) (ABI) today announced filing of an IND application for a pivotal Phase III trial to test low-dose interferon alpha lozenges administered orally to human immunodeficiency virus (HIV)-positive subjects with oral warts.
O'Brien's study follows a British report that concluded highly active antiretroviral therapy appears to increase the frequency of oral warts (Lancet 357[9266]: 1,411-12, 2001).
A review of the records from 1280 patients with HIV seen at a clinic between 1990 and 1999 indicates that the frequency of oral warts is increasing, despite the use of anti-HIV therapy.
In the United States, four new clinical sites have been opened to enroll patients in a Phase 2 clinical trial of oral warts.
announced today that it has commenced Phase II clinical trials for a proprietary formulation of a low dose oral interferon-alpha product for the treatment of oral warts caused by human papilloma virus (HPV) in HIV-infected patients.
The clinic also provides a unique experience for patients to participate in several research studies looking at topics like oral warts, oral Epstein-Barr virus infections, the effects and treatment of lipodystrophy in the oral cavity, and dental implants.
While the development of new antiretroviral therapies for the management of HIV infection, particularly protease inhibitors, has resulted in a decreased prevalence of certain oral diseases such as hairy leukoplakia and necrotizing periodontitis, a paradoxical increase in oral warts has been observed.
Amarillo Biosciences has a Phase 2 clinical investigation using oral low-dose interferon-alpha for Behcet's disease and a Phase 2 clinical trial to treat oral warts in HIV-positive patients now underway.
Food and Drug Administration (FDA) to proceed into human clinical studies with a low dose oral interferon-alpha product for the treatment of oral warts caused by human papilloma virus (HPV) in HIV-infected patients.
Oral warts are severe, chronic, debilitating and disfiguring with no existing satisfactory treatment.
The Company has a Phase 2 clinical investigation using oral low-dose interferon-alpha for Behcet's disease now underway and plans to begin enrollment in a Phase 2 clinical trial in December to treat oral warts in HIV-positive patients.
Nasdaq: AMAR) today announced that its Board of Directors approved funding for pilot clinical trials testing the company's low dose oral interferon alpha in HIV positive patients infected by oral warts.