optic neuropathy


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Related to optic neuropathy: optic neuritis, Ischemic optic neuropathy

optic neuropathy

Etymology: Gk, optikos, sight, neuron, nerve, pathos, disease
a disease, generally noninflammatory, of the eye, characterized by dysfunction or destruction of the optic nerve tissues. Causes include an interruption in the blood supply, compression by a tumor or aneurysm, a nutritional deficiency, and toxic effects of a chemical. The disorder, which can lead to blindness, usually affects only one eye.

optic neuropathy

Pathological injury to the optic nerves or the blood supply to them. Usually, only one eye is affected. Several forms have been described, including ischemic optic neuropathy, which, if prolonged, leads to blindness in the affected eye; optic neuritis due to acute demyelination of optic nerve fibers; infiltrative optic neuropathy, in which the optic nerve is compressed by a tumor or aneurysm; and optic neuropathy due to toxic nutritional factors, e.g., methanol or a combined nutritional and vitamin deficiency.
See also: neuropathy

neuropathy, optic

A non-inflammatory or degenerative disease of the optic nerve. See ophthalmopathy.
References in periodicals archive ?
Stem Cell Ophthalmology Treatment Study: bone marrow derived stem cells in the treatment of non-arteritic ischemic optic neuropathy (NAION).
Santhera's lead product Raxone (idebenone) is authorized in the European Union, Norway, Iceland, Liechtenstein and Israel for the treatment of Leber's hereditary optic neuropathy (LHON).
Non-arteritic anterior ischemic optic neuropathy is the most common acute unilateral optic neuropathy in persons over the age of 50.
Histopathologic studies of ischemic optic neuropathy.
She was diagnosed with optic neuropathy, and her vision deteriorated within three days.
The report provides a snapshot of the global therapeutic landscape of Leber's Hereditary Optic Neuropathy (LHON) (Leber optic atrophy)
Those complications of radiotherapy may cause blindness as a result of radiation retinopathy, optic neuropathy, or enucleation of the eye due to scleral necrosis.
The second aim of this study was to investigate the presence of subclinical optic neuropathy in neurologically and ophthalmologically asymptomatic HCV-infected subjects.
Occurrence of a multiple sclerosis-like illness in women who have a Leber's hereditary optic neuropathy mitochondrial DNA mutation," Brain, vol.
3] however, in contrast, one patient presented with optic neuropathy in our study.
Pre-excitation syndrome is common in families with Leber hereditary optic neuropathy (LHON) [1].
The valuation is based on the Company's lead compound Raxone/Catena (INN: idebenone) as the key value driver in its first two indications: Leber's Hereditary Optic Neuropathy (LHON) and Duchenne Muscular Dystrophy (DMD).