opsonic


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Related to opsonic: opsonic index

op·son·ic

(op-son'ik),
Relating to opsonins or to their use.

opsonic

(ŏp-sŏn′ĭk)
adj.
Of, relating to, or produced by opsonins.

op·son·ic

(op-son'ik)
Relating to opsonins or to their utilization.

opsonin

(ŏp-sō′nĭn) [Gr. opsonein, to purchase food]
A substance that coats foreign antigens, making them more susceptible to macrophages and other leukocytes, thus increasing phagocytosis of the organism. Complement and antibodies are the two main opsonins in human blood. opsonic (-sŏn′ĭk), adjective

immune opsonin

Opsonin formed after stimulation by a specific antigen.
References in periodicals archive ?
falciparum infection has been attributed to the impaired opsonic phagocytic clearance of malaria parasites, especially in multigravid women (33,46), and reduced levels of specific antibodies associated with protection against malaria in pregnancy.
In cirrhotic patients, the bactericidal and opsonic activity of the ascitic fluid is lower than that observed in noncirrhotic ascites or in normal peritoneal exudate (3,12,13) Recent investigations have shown that cirrhotic patients with low ascitic fluid C3 and low ascitic fluid total protein are more predisposed to SBP.
A transient bacteraemia that infects the pleural space could be the underlying pathogenic mechanism apart from the impaired opsonic activity of the pleural fluid.
Previous investigators have also reported that the N-terminal regions of M proteins possess functional domains in addition to opsonic epitopes that might constrain the amount of variability within an M type (30-33).
Further studies have shown that the particular opsonic defect predisposes to respiratory infection, diarrhoea, atopy and failure to thrive during infancy (28-31).
14) Patients with cirrhosis of the liver have depressed reticuloendothelial activity, decreased ascitic-fluid opsonic activity bowel wall edema, and bacterial colonization of the small bowel (15) moreover, there is decreased clearance of bacteria from the blood stream in these patients.
Tripep has out licensed the RAS[R] technology to Opsonic Therapeutics
The classical complement pathway and heat-stable opsonins are required for maximal opsonic activity against the major serotypes of CBS.
STOCKHOLM, Sweden -- Tripep (STO:TPEP) and the German biotech company Cosmix AG have both licensed their respective technologies (RAS and mRNA Display Library) to a newly formed US company named Opsonic Therapeuticals Inc.
Dale reported that rabbits given the prototypic group A streptococcus vaccine developed high levels of opsonic (protective) antibodies against six targeted strains of group A streptococcus.