HIV impairs opsonic
phagocytic clearance of pregnancy-associated malaria parasites.
In cirrhotic patients, the bactericidal and opsonic activity of the ascitic fluid is lower than that observed in noncirrhotic ascites or in normal peritoneal exudate (3,12,13) Recent investigations have shown that cirrhotic patients with low ascitic fluid C3 and low ascitic fluid total protein are more predisposed to SBP.
Akalin HE, Laleli Y, Telatar H: Bactericidal and opsonic activity of ascitic fluid from cirrhotic and noncirrhotic patients.
Once MBL deficiency had been identified and MBL became available in therapeutic quantities, reconstitution of patients with opsonic
defects and abnormal infections can become feasible.
Patients with ascitic total-protein levels of less than 1 g/dL are at high risk of SBP due to decreased ascitic-fluid opsonic
The classical complement pathway and heat-stable opsonins are required for maximal opsonic
activity against the major serotypes of CBS.
STOCKHOLM, Sweden -- Tripep (STO:TPEP) and the German biotech company Cosmix AG have both licensed their respective technologies (RAS and mRNA Display Library) to a newly formed US company named Opsonic
Dale reported that rabbits given the prototypic group A streptococcus vaccine developed high levels of opsonic
(protective) antibodies against six targeted strains of group A streptococcus.
Lucas, a specialist in the company's immune technology, show that when Immuno-C(tm) is mixed with bacteria and polymorphonuclear cells from bovine, equine or human blood, the drug has opsonic
ability to stimulate immune response, and thus to help eliminate disease.