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oncofetal

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oncofetal /on·co·fe·tal/ (-fe´t'l) carcinoembryonic.
on·co·fe·tal (ngk-ftl)
adj.
Of or relating to substances associated with tumor formation and present in fetal tissue.


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The company's research is focused on the use of the oncofetal antigen ("OFA"), or more specifically, iLRP - immature Laminin Receptor Protein, as a cancer immunogen (a cancer target against which the immune system is directed) found in many tumor cell lines or fetal tissue, but not found in normal mature tissue.
HMB-45 is an antibody that reacts with an oncofetal premelanosome-associated glycoprotein 2, found in neoplastic (but not normal) melanocytes, as well as other cells bearing those structures.
[FIGURE 2 OMITTED] D2-40, a novel monoclonal antibody that was initially raised against an oncofetal antigen M2A, (41) was recently introduced to diagnostic pathology to help identify lymphatic endothelium.
 
 
 
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