A case of acquired renal cystic disease (ACDK) with oncocytosis, a dominant nodule (oncocytoma), multiple adenomas and a microscopic papillary renal cell carcinoma associated with crescentic glomerulonephritis.
Renal oncocytosis and multiple papillary adenomas with oncocytoma as dominant nodule coexisting with papillary carcinoma in a patient with diabetic glomerulosclerosis, acquired renal cystic disease and B cell lymphoma.
In the first large series on hybrid tumors, Tickoo et al (13) reported on a group of patients with renal oncocytosis
, some of whom developed tumors with hybrid morphologies.
In this regard, Brandwein and Huvos (1) found a history of radiation exposure in some of their cases, and Becker et al (14) described an age-dependent intracellular metabolic defect associated with mitochon driopathy as an explanation for the development of oncocytosis in 2 of their cases.
15) The WHO groups these tumors into three distinct categories: diffuse oncocytosis, multifocal nodular oncocytic hyperplasia (MNOH), and oncocytomas (benign and malignant).
1) These tumors are classified as one of three types: diffuse oncocytosis, focal adenomatous oncocvtic hyperplasia, and oncocytoma.
Oncocytomas may be multifocal or bilateral, and as many as 7% of cases may represent diffuse oncocytosis rather than a single mass.
Diffuse hyperplastic oncocytosis of the parotid gland.
The case reported by Leroy et al (1) describes an association between oncocytosis and renal failure in a patient in whom a papillary renal cell carcinoma was also present.
Bilateral renal oncocytosis with renal failure: immunohistochemical and cytogenetic study of a case associated with a papillary renal cell carcinoma.
We present a new case of oncocytosis associated with a papillary renal cell carcinoma.
2-7] Recently, Tickoo et al reported a series of 14 cases and proposed the term oncocytosis.