oligonucleotide


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oligonucleotide

 [ol″ĭ-go-noo´kle-o-tīd]
a polymer made up of a few (2 to 10) nucleotides.

ol·i·go·nu·cle·o·tide

(ol'i-gō-nū'klē-ō-tīd),
A compound made up of the condensation of a small number (typically fewer than 20) of nucleotides. Compare: polynucleotide.

oligonucleotide

/ol·i·go·nu·cle·o·tide/ (ol″ĭ-go-noo´kle-o-tīd) a polymer made up of a few (2–20) nucleotides.

oligonucleotide

(ŏl′ĭ-gō-no͞o′klē-ə-tīd, -nyo͞o′-, ō′lĭ-)
n.
A short polymer of two to twenty nucleotides.

oligonucleotide

[-no̅o̅′klē·ətīd′]
a compound formed by linking a small number of nucleotides.

ol·i·go·nu·cle·o·tide

(ol'i-gō-nū'klē-ō-tīd)
A compound made up of the condensation of a small number (typically fewer than 20) of nucleotides.
Compare: polynucleotide

oligonucleotide

a short sequence of NUCLEOTIDES. Compare POLYNUCLEOTIDE.

ol·i·go·nu·cle·o·tide

(ol'i-gō-nū'klē-ō-tīd)
A compound made up of the condensation of a small number of nucleotides.

oligonucleotide,

n a compound made up of the condensation of a small number of nucleotides.

oligonucleotide

a polymer made up of a few to a hundred or more nucleotides. Can be made synthetically to a specified sequence.

oligonucleotide ligation assay
a technique for detecting a specific nucleotide pair in a gene.
References in periodicals archive ?
Experiments are underway to narrow the 200-bp region of binding by using small overlapping oligonucleotides from the region and to test binding with nuclear extracts from non-hematopoietic cell lines.
The TPP oligonucleotide contained the 3'-PDGF-BB aptamer sequence, a C1o spacer, and a 10-base 5' reporter sequence (complementary to the reporter sequence of the AzC oligonucleotide) containing the 5' TPP group.
The Oligonucleotide Production Suite is equipped with the latest technology that allows small to large scale Oligo production and purification capabilities.
The use of common technology platforms, from pre-clinical to launched product, will enable oligonucleotide drug developers to benefit from regulatory simplicity, cost control, time savings and risk minimization, particularly in the important pre-clinical to clinical transition.
Under the agreement terms, the two companies will collaborate in synthesizing high-reactive aminated oligonucleotide using the newly-developed amination reagent.
The kidney is the primary site of oligonucleotide distribution in both rodents and nonhuman primates and thus is the potential target organ for toxicity in these species.
Next, the cells containing the CORE cassette are transformed with oligonucleotides that are designed to contain the chosen modification, a process that yields the desired deletion, insertion, or mutation.
The experimental compound is an oligonucleotide that's been altered to make it resist degradation -which would kill its effectiveness -- once it gets inside an HIV-infected cell.
About Immune Modulatory Oligonucleotide (IMO([R])) Technology Patent Portfolio
According to the new research report " Oligonucleotide Synthesis Market by Product & Services (Equipment, Reagent, Primer, Probe, Custom Oligos), End-User (Research, Pharmaceutical & Biotechnology), Application (Diagnostics, PCR, QPCR, Gene Synthesis, NGS, DNA, RNA i ) - Global Forecast to 2019 " published by MarketsandMarkets, the global Oligonucleotide Synthesis Market is expected to reach $1,712.
has given two presentations of preclinical data that suggest its novel second-generation immunomodulatory oligonucleotide (IMO) compounds have potent therapeutic benefits in a mouse model of established allergic asthma.