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oligomycin

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oligomycin
inhibitor of oxidative phosphorylation, acting at the O-sensitivie subunit of F0F1-ATPase.


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Oligomycin hampers the oxidation of pyruvate and when added to the cell, it switches off the current.
Subsequent experiments with the F1F0-ATPase inhibitor oligomycin (5 [micro]g/ml) were performed to check whether a possible drop in the RCR derives from uncoupling or increased intramitochondrial metabolism of ATP.
05 Saline Monocrotaline 5 50 Saline Nicotinic acid 200 2,000 Saline Oligomycin 0.
 
 
 
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