In addition, we performed variance component analysis and hypothesis testing with Sequential Oligogenic
Linkage analysis Routines (SOLAR) (Almasy and Blangero 1998) to evaluate the significance and standard error for each heritability.
This provides evidence that some cases of familial transposition are caused by mutations in laterality genes and therefore are part of the same disease spectrum of heterotaxy syndrome, and argues for an oligogenic
or complex mode of inheritance in these pedigrees.
The heritability of GDF15 was estimated with variance component models that use Sequential Oligogenic
Linkage Analysis Routines (22).
Because this kind of resistance is controlled by more than one gene, in other words is oligogenic
or polygenic .
Genes that determine gender are of 2-factor oligogenic
and polygenic systems.
These observations point towards a combination of Mendelian autosomal recessive transmission, with more complex oligogenic
Digenic or oligogenic
inheritance has been reported, as some patients carry 2 or even 3 mutations in more than one related genes.
pattern may exist in which more than one gene collaborates to produce a phenotype or a heterogeneity in which similar phenotypes may arise from different genotypes.
resistance to powdery mildew in mungbean with RFLPs.
Single-gene inheritance (and the individual genes that contribute to an oligogenic
or multifactorial phenotype) can be autosomal recessive, autosomal dominant, additive (codominant), sex-chromosome linked, or mitochondrial.
We estimated the heritability of %iAs, %MMA, and %DMA using a general pedigree variance components decomposition-based method as conducted by the software Sequential Oligogenic
Linkage Analysis Routines (SOLAR) version 4.
combinations associated with breast cancer risk in women under 53 years of age.