olfactory ensheathing cell


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olfactory ensheathing cell

A glial cell of neural crest origin that participates in the growth and guidance of primary neurons in the olfactory bulb and olfactory epithelium. OECs have a short (6 to 8 week) lifespan and are replaced by differentiated stem cells in the region. Growth and regeneration of olfactory axons is attributed to OECs, which form bundles through which axons grow from the periphery into the CNS, guided by the glial composition and cytoarchitecture of the olfactory bulb and OECs. OEC transplantation to sites of spinal cord injuries in dogs has been successfully used to restore function; it has not been tried in human trials.
References in periodicals archive ?
Nasal olfactory ensheathing cells transplants assist recovery after spinal cord injury, including complete transaction (34,35) and there is evidence that adult olfactory tissue is effective when transplanted one month after spinal cord transaction in the rat (36).
Identification of a human olfactory ensheathing cell that can effect transplant-mediated remyelination of demyelinated CNS axons.
In another strategy, they investigated the ability of special nurse-like cells called olfactory ensheathing cells to prevent the death of neurons that follows axonal injury.
Samuil Rabinovich (Russia), fetal olfactory ensheathing cells (OECs), nerve, and hematopoietic tissues
This tissue is rich in regenerating neurons, stem cells, and olfactory ensheathing cells (OECs).
In some patients, Bryukhovetskiy has transplanted autologous olfactory ensheathing cells (OECs) using procedures developed by England's Dr.
Because olfactory tissue is exposed to the air we breathe, it contains cells with considerable turnover potential, including renewable neurons, progenitor stem cells, and olfactory ensheathing cells (OECs) (see March 2003 PN).
Currently, one of the most talked about therapies involves the transplantation of olfactory ensheathing cells (OECs).
Implanting a Schwann-cell bridge and olfactory ensheathing cells leads to growing cells.
The axons come together to form bundles (fascicles) that are enveloped by olfactory ensheathing cells (OECs), a special type of glial or neuronal support cell that guides the axon and supports its elongation.
Susan Barnett (Glasgow, United Kingdom) reviewed research on transplanting olfactory ensheathing cells (OECs) into the injury site.
Kocsis on a project using human olfactory ensheathing cells to remyelinate the demyelinated rat spinal cord.