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ochronosis |
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ochronosis /ochro·no·sis/ (o″kron-o´sis) deposition of dark pigment in the body tissues, usually secondary to alkaptonuria, characterized by urine that darkens on standing and dusky discoloration of the sclerae and ears.ochronot´ic
ochronosis People with this rare hereditary condition tend to develop arthritis in adulthood. Mentioned in: Pseudogout ochronosis [ō′krənō′sis] Etymology: Gk, ochros, yellow, osis an inherited error of protein metabolism characterized by an accumulation of homogentisic acid, resulting in degenerative arthritis and brown-black pigment deposited in connective tissue and cartilage. It is often caused by alkaptonuria or poisoning with phenol. Bluish macules may be noted on the sclera, fingers, ears, nose, genitalia, buccal mucosa, and axillae. Urine color may be dark. See also alkaptonuria. ochronosis (ōˈ·kr n condition marked by accumulation of black-brown pigment in cartilage, joint capsules, and other connective tissues as a result of alkaptonuria, which is a metabolic disorder resulting in accumulation of homogentisic acid. See also alkaptonuria. ochronosis a yellow, brown or chocolate discoloration of cartilage, tendon sheaths and ligaments but not bone. Caused by deposit of alkapton bodies as the result of a metabolic disorder. Affected parts must be condemned as not suitable for human consumption. ocular ochronosis brown or gray discoloration of the sclera, sometimes involving also the conjunctivae and eyelids. ochronosis Alkaptonuria, see there How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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