octreotide


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octreotide

 [ok-tre´o-tīd]
a synthetic analogue of somatostatin, used as the acetate ester in palliative treatment of symptoms of gastrointestinal endocrine tumors and in treatment of acromegaly; administered subcutaneously, intragluteally, or intravenously.

oc·tre·o·tide

(ok'trē-ō-tīd),
Somatostatin analogue used to treat secretory diarrheal states and gastrointestinal bleeding.

octreotide

/oc·tre·o·tide/ (ok-tre´o-tīd) a synthetic analogue of somatostatin, used as the acetate ester in the palliative treatment of the symptoms of gastrointestinal endocrine tumors and in the treatment of acromegaly.

octreotide

an antidiarrheal and hormone.
indications The two brand names of this drug are used for different purposes. Sandostatin is used to treat acromegaly, carcinoid tumors, and vasoactive intestinal peptide tumors (VIPomas). Sandostatin LAR Depot is used for long-term maintenance of acromegaly, carcinoid tumors, and VIPomas.
contraindications Known hypersensitivity to this drug prohibits its use.
adverse effects Life-threatening effects include seizure, arrhythmias, congestive heart failure, hepatitis, GI bleeding, and pancreatitis. Other adverse effects are depression, anxiety, tremors, paranoia, chest pain, shortness of breath, thrombophlebitis, ischemia, hypertension, palpitations, galactorrhea, diabetes insipidus, increased liver function tests, urinary tract infection, pollakiuria, hematoma and inflammation of the injection site, bruising, rash, urticaria, and pain. Common side effects include headache, dizziness, fatigue, weakness, sinus bradycardia, conduction abnormalities, hyperglycemia, ketosis, hypothyroidism, hypoglycemia, diarrhea, nausea, abdominal pain, vomiting, flatulence, distension, constipation, and joint and muscle pain.

octreotide

An hormone inhibitor analogue of the natural substance SOMATOSTATIN. Octreotide has a much longer effective time of action than somatostatin and is selective in its action on secretion of growth hormone, GASTRIN, SECRETIN and MOTILIN. It is also effective against various tumours of the ENDOCRINE system. A brand name is Sandostatin.

octreotide

a somatostatin analog used in the treatment of endocrine disorders of the pituitary and pancreas.
References in periodicals archive ?
com/research/z9wpj6/investigation) has announced the addition of the "Investigation Report on China's Octreotide Market, 2010-2019" report to their offering.
111]In octreotide scintigraphy showed increased uptake of the nodule (Figure 1B, arrow).
He said the Octreotide Scan is a type of scintigraphy used to diagnose carcinoid and pancreatic neuroendocrine tumors using SPECT CT scan.
Octreotide scan did not show significant uptake within these lesions.
Octreotide scan was also performed looking for a carcinoid tumor.
An infusion of octreotide was administered at 1-5 [micro]g/kg in a 5% dextrose solution at 5 ml/ hour, in decreasing doses over 4-5 days.
111]In-labeled diethylenetriamine pentaacetic acid octreotide ([sup.
We started an octreotide infusion at 2 mg/kg/hour and planned to give this for 5 days as suggested in the literature when chylous ascites was over 10 liters.
He uncovered a breakthrough drug used in a Greek trial called Octreotide and persuaded health bosses to fund the pounds 28-a-day treatment.
A randomized, double-blind, placebo-controlled, multicenter phase III trial of everolimus + octreotide LAR vs placebo + octreotide LAR in patients with advanced neuroendocrine tumors (NETHRADIANT-2) (8)
The new drug works by blocking a protein known as mTOR and is given in combination with Novartis's older drug Sandostatin, or octreotide LAR.