octacosanol

octacosanol

a dietary supplement. Also called 1-octacosanol.
uses It is used for herpes, inflammation of the skin, amyotrophic lateral sclerosis (ALS), and physical endurance. It is probably not effective for ALS, and there are insufficient reliable data for other indications.
contraindications Octacosanol should not be used during pregnancy and lactation or in children.

octacosanol

A straight-chain, aliphatic 28-carbon fatty alcohol found in wheat germ and epicuticular waxes of plants—e.g., Eucalyptus species, forage and cereal grasses (e.g., Acacia, Trifolium, Pisum and other legume genera).

octacosanol (äkˈ·t·kōˑ·s·näl),

n waxy substance derived from wheat germ and sugar cane. Has been used as an athletic performance enhancer and a potential treatment for Parkinson's disease and amyotrophic lateral sclerosis.
References in periodicals archive ?
Recently, an octacosanol isolated from rice bran has been reported to improve growth performance, enhance immunity and anti-oxidant status, and significantly reduce diarrhea of weanling piglets (Long et al.
Caption: Figure 2: The cytotoxic effects of carvacrol, thymol, p-cymene, and 1- octacosanol in A549 cells.
Other substances touted as having ergogenic properties are carnitine, cobamamide, growth hormone releasers, octacosanol, and ginseng, but there is no reliable scientific evidence to support claims that products containing these compounds have ergogenic potential, and heavy supplementation may lead to adverse effects.
Literature survey revealed the presence of diterpenoids [7], triterpenoids [8], flavonoids [9] and chromone glucosides [10] from different species of the genus Chrozophora and C12-C30 hydrocarbons, cholesterol, stigmasterol, B-sitosterol, B-amyrin, squalin, octacosanol, hexacosanol and tetracosanol from Chrozophora plicata [11].
Octacosanol isolated from Tinospora cordifolia downregulates VEG F gene expression by inhibiting nuclear translocation of NF-[alpha] and its DNA binding activity.
Active antioxidants such as lecithin and octacosanol from whole grains; polyphenols and sterols contained in fruits and vegetables; lycopene and other phytochemicals from tomatoes; sulfur/allicin from onions and garlic; pectin, rutin and quercetin from apples; phytocyanidins and antioxidant flavonoids such as apigenin and luteolin from various greenfoods; and anthocyanins from various fruits and oats are all antioxidants known for cardiovascular benefits.
One of complementary medicine's greatest unacknowledged supplements is wheat germ, the source from which we derive octacosanol.
Apple, 1 medium Ellagic acid, octacosanol, quercetin
The use of octacosanol has been investigated by Lazarus A.
1993), octacosanol has been widely applied to health food, functional beverage, medicine and other fields.
An "energy factor," octacosanol, derived from wheat, can be very beneficial.