nucleotide-binding oligomerization domain protein


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nucleotide-binding oligomerization domain protein

Abbreviation: NOD
Any of a family of cytoplasmic proteins that recognize molecules associated with disease-causing bacteria and stimulate cells to secrete cytokines and costimulatory molecules. Inappropriate regulation of nucleotide-binding oligomerization domain proteins has been linked to the pathogenesis of Crohn's disease and other syndromes.
See also: protein
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