nucleotide


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nucleotide

 [noo´kle-o-tīd]
any of a group of compounds obtained by hydrolysis of nucleic acids, consisting of a purine or pyrimidine base linked to a sugar (ribose or deoxyribose), which in turn is esterified with phosphoric acid.
cyclic n's those in which the phosphate group bonds to two atoms of the sugar forming a ring, as in cyclic AMP and cyclic GMP, which act as intracellular second messengers.

nu·cle·o·tide

(nū'klē-ō-tīd),
Originally a combination of a (nucleic acid) purine or pyrimidine, one sugar (usually ribose or deoxyribose), and a phosphoric group; by extension, any compound containing a heterocyclic compound bound to a phosphorylated sugar by an N-glycosyl link (for example, adenosine monophosphate, NAD+). For individual nucleotides see specific names.
Synonym(s): mononucleotide

nucleotide

/nu·cleo·tide/ (noo´kle-o-tīd″) one of the compounds into which nucleic acid is split by action of nuclease; nucleotides are composed of a base (purine or pyrimidine), a sugar (ribose or deoxyribose), and a phosphate group.
cyclic nucleotides  those in which the phosphate group bonds to two atoms of the sugar forming a ring, as in cyclic AMP and cyclic GMP, which act as intracellular second messengers.

nucleotide

(no͞o′klē-ə-tīd′, nyo͞o′-)
n.
Any of a group of compounds consisting of a nucleoside combined with a phosphate group and constituting the units that make up DNA and RNA molecules.

nucleotide

[no̅o̅′klē·ətīd′]
a compound consisting of one or more phosphate groups, a pentose sugar, and a nitrogenous base. Chains of nucleotides form DNA and RNA; free nucleotides, such as adenosine triphosphate and guanosine triphosphate, are important energy carriers in all cells.

nu·cle·o·tide

(nū'klē-ō-tīd)
A combination of a (nucleic acid) purine or pyrimidine, one sugar (usually ribose or deoxyribose), and a phosphoric group.
Synonym(s): mononucleotide.

nucleotide

A molecule formed from the bonding of a purine or a pyrimidine base with a sugar and a mono-, di- or tri-phosphate group. Compare NUCLEOSIDE. Four different nucleotides may polymerize to form DNA. They are 2'-deoxyadenosine 5'-triphosphate; 2'-deoxyguanosine 5'-triphosphate; 2'-deoxycytidine 5'-triphosphate; and 2'-deoxythymidine 5'-triphosphate. These lengthy names are commonly abbreviated to dATP, dGTP, dCTP and dTTP. Even this is too clumsy when printing out the sequence of nucleotides in a length of DNA. In that case they are abbreviated to A, G, C and T (for adenine, guanine, cytosine and thymine). In RNA the sugar is not 2'-deoxyribose, but ribose itself. Also one of the RNA bases differs from that in DNA. Thymine is replaced by uracil. So the nucleotides of RNA are adenosine 5'-triphosphate; guanosine 5'-triphosphate; cytidine 5'-triphosphate; and uridine 5'-triphosphate. These are abbreviated to ATP, GTP, CTP and UTP or simply A, G, C and U.
Nucleotideclick for a larger image
Fig. 232 Nucleotide . Basic units of (a) deoxyribose sugar, (b) phosphate. Each carbon atom is numbered (1 prime, 2 prime, etc).
Nucleotideclick for a larger image
Fig. 233 Nucleotide . Linkage of the three nucleotide elements.

nucleotide

a complex organic molecule forming the basic unit of NUCLEIC ACIDS, with a structure made up of three components: a pentose sugar (ribose, or deoxyribose with one less oxygen atom), an organic base (PURINE type: ADENINE and GUANINE; or PYRIMIDINE type: CYTOSINE, THYMINE and URACIL) and a phosphate group (see Fig. 232 ). The three elements are linked together by two condensation reactions between the 1 sugar carbon and a base forming a NUCLEOSIDE, and the 5' sugar carbon and the phosphate (see Fig. 233 ). The nucleotides are formed into POLYNUCLEOTIDE CHAINS.

Nucleotide

Any of a group of organic molecules that link together to form the building blocks of DNA or RNA.
Mentioned in: Myotonic Dystrophy

nucleotide

combination of nucleic acid, purine or pyramidine, sugar (ribose or deoxyribose) and a phosphate group

nucleotide

any of a group of compounds obtained by hydrolysis of nucleic acids, consisting of a purine or pyrimidine base linked to a sugar (ribose or deoxyribose), which in turn is esterified with phosphoric acid. See also nucleoside, deoxyribonucleic acid.

cyclic n's
those in which the phosphate group bonds to two atoms of the sugar forming a ring, as in cyclic AMP and cyclic GMP, which act as intracellular second messengers.
nucleotide sequences
see dna sequencing.
single nucleotide polymorphisms (SNPs)
single base pair changes that distinguish one individual from another of the same species.
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Grand View Research has segmented the global nucleotide market on the basis of technology, ingredients, application and region:
The nucleotide differences among examined Cladosporium species showed lower variations where it was only 4 nucleotides differences between Cl.
the document nucleotide does not match the query nucleotide identically.
A map of human genome sequence variation containing 1,42 million single nucleotide polymorphisms.
Chapter Five Nucleotide Manufacturing Process and Cost Structure
32]P-end labeling and annealed to the complementary DNA (see Figure 1A for nucleotide sequences).
In 1991 and 1992, Gilead entered into license agreements with IOCB and the Rega Institute for Medical Research, Katholic University in Leuven, Belgium that cover a large number of nucleotide analogue compounds and structures.
Phase 1 combination study of a pyrimidine (PSI-7977) and purine (PSI-938) nucleotide analog in patients with chronic hepatitis C
This strain showed 93%-94% and 96%-97% identity at the nucleotide and amino acid level, respectively, which suggests a sufficient antigenic community.
Johnston, IA) has patented a composition and method for regulating expression of heterologous nucleotide sequences in a plant.
To cope with the complexities of repetitive DNA elements and to assemble the thousand-base reads in the correct long-range order across the genome, current genomic sequencing methods involve a variety of additional strategies, such as the sequencing of both ends of cloned DNA fragments, use of libraries of cloned fragments of different lengths, incorporation of map information, achievement of substantial redundancy (multiple reads of each nucleotide from overlapping fragments) and application of sophisticated assembly algorithms to align and filter the read information.