nucleosome


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nucleosome

 [noo´kle-o-sōm″]
any of the complexes of histone and DNA in eukaryotic cells, seen under the electron microscope as beadlike bodies on a string of DNA.

nu·cle·o·some

(nū'klē-ō-sōm'),
A localized aggregation of histone and DNA that is evident when chromatin is in the uncondensed stage.
Synonym(s): nu body
[nucleo- + G. sōma, body]

nucleosome

/nu·cleo·some/ (-sōm) any of the complexes of histone and DNA in eukaryotic cells, seen under the electron microscope as beadlike bodies on a string of DNA.

nucleosome

(no͞o′klē-ə-sōm′, nyo͞o′-)
n.
Any of the repeating subunits of chromatin found in eukaryotes, consisting of a DNA chain coiled around a core of histones.

nu′cle·o·som′al (-sō′məl) adj.

nucleosome

[no̅o̅′klē·əsōm′]
Etymology: L, nucleus + Gk, soma, body
any one of the repeating DNA-histone complexes that appear as beadlike structures at distinct intervals along a chromosome.

nucleosome

A nucleic acid and protein complex, which is the basic structural unit of chromatin, composed of a segment of DNA wrapped around a core of histone molecules.

nu·cle·o·some

(nū'klē-ō-sōm)
A localized aggregation of histone and DNA that is evident when chromatin is in the uncondensed stage.
[nucleo- + G. sōma, body]

nucleosome

The structural subunit of CHROMATIN consisting of about 200 BASE PAIRS and a barrel-shaped core of eight histone protein molecules (an octamer).

nucleosome

the basic structural unit of the eukaryote chromosome, being composed of four pairs of HISTONE proteins (H2A, H2B, H3 and H4) that are combined to form an octomer around which is wrapped about 150 nucleotide pairs of DNA.

nucleosome

any of the complexes of histone and DNA in eukaryotic cells, seen under the electron microscope as beadlike bodies on a string of DNA.
References in periodicals archive ?
For example, PICKLE (PKL), a plant homologue of the animal chromatin remodeling factor CHROMODOMAIN/HELICASE/DNA-BINDING DOMAIN 3/Mi-2 (CHD3/Mi-2) which functions as a subunit of NUCLEOSOME REMODELING and DEACETYLASE (NuRD) repressive complex as well as PICKLE RELATED 2 (PKR2) have trithomx-like functions, while CURLY LEAF (CLF) which is known to mediate the Irimethylation of H3K27 is a polycomb group protein.
The histones making up the core of the nucleosome have unstructured N-terminal tails that protrude from the nucleosome and which are subject to modifications.
Several of the peaks can be interpreted in terms of the known biochemistry of the nucleosome, and owing to the genetic differences between donor and recipient, Lo's group is able to report that circulating cell-free DNA is primarily hematopoietic in origin.
Nucleosomes are considered to be the basic element of chromatin.
One class of histones, known as the H1 or linker histones, bind to DNA to stabilize two full turns of DNA around the nucleosome core.
1972), which is characterized by cleavage at nucleosome linker regions, producing 180-200 base pair fragments (see Lo et al.
gene heredity mutation mitosis embryo allele helix clone sequence polymer autosome phenotype recessive metaphase locus polymerase telophase oligonucleotide geneticist interphase prophase phage bacteriophage chromomere transduction transformation nucleus Mendelian genome meiosis chromosome recombinant pedigree plasmid vector replicon nucleosome chromatography zygote centromere anaphase genotype endonuclease backcross exonuclease polyploidy diakinesis cytogenetics crossover segregate codominance dominance translocation nucleolus
A notable number of the sequenced mutations map to looped regions of H3 that are believed to serve as DNA docking sites on the nucleosome, suggesting that specific contacts between the DNA and the nucleosome core particle can influence chromatin structure.
Histone tails protrude from the nucleosome structure and are subject to a variety of post-translational modifications on multiple residues, including methylation, acetylation, phosphorylation, sumoylation, ubiquitination and polyribosylation.
Twenty-five years of the nucleosome, fundamental particle of the eukaryotic chromosome.
Epigenetics encompasses regulatory networks involving DNA methylation, histone modification, nucleosome location, and noncoding RNA--a complexity of chemical switches determining gene expression.